Bob (Robert) ROBINSON   
                       
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Meet the Lab


BR Lab Photos

Tropical BR Lab Christmas Party – Dec. 2015

Typical BR Lab Meeting – Dec. 2015

Pursuing the perfect Pla Pao - Golden Mile - Summer 2014

Leaving no leaf unturned - Samy's - summer 2013


Research Scientists

 

Bo XUE
bxue@imcb.a-star.edu.sg

Candied Chinese hawthorns on a bamboo skewer are my favorite, as the sweet and sour taste always gives me a good appetite.  The projects I get from the lab are quite tasty too, so I can’t help taking them one after another.  And that’s why I’ve been here for so many years...

 



 

David POPP
dpopp@imcb.a-star.edu.sg

David started his quest to understand the cells physiologically relevant biological filament systems and the search for Nature’s primordial actin- and microtubule-like filaments over 30 years ago at the MPI for Medical Research in Heidelberg where he solved the structure of one of Nature’s most abundant filaments, F-actin together with Ken Holmes. He has worked at Brandeis University with Hugh Huxley on muscle acto-myosin filament contraction using electron microscopy and at Spring8, Japan with Yuichiro Maeda on bacterial filament systems, before joining IMCB in 2009. His main drive at present is to solve structures of DNA segregating polymers by cryo-electron microscopy and to use these systems as biological nano-machines and nano-wires.

In his spare time, David is a fly fisherman, fly tier, fly caster and bamboo fly rod maker. His next destination: Jurassic lake, Patagonia

 


 

Postdoctoral Fellows

 

Shi Min JIANG
smjiang@imcb.a-star.edu.sg

Hi I’m Shimin!
I was very happy and lucky to join Bob’s lab at August, 2011. Here, I focus on the bacterial filament systems with Dr David. These filament systems play a key role in the life cycle of bacteria, including many pathogenic bacteria. Although there’s still a long, long way to go, our final target is to uncover the mechanism of filament systems and find new antibiotics targeting these systems.  After working, I like cooking, eating, drinking, watching movie, cycling and playing badminton. Anyway, I am very enjoying my studies and research in this fantastic team.

 


 

Wei Lin LEE
wlee@imcb.a-star.edu.sg

As the adage goes - choose a job you love, and you will never have to work a day in your life. This pretty much sums up life in BR lab for me. I did my undergraduate in National University of Singapore; and with a scholarship from A*STAR I did my D.Phil at Oxford University. During my DPhil, I was intrigued by how a great number of disease-causing bacteria have evolved mechanisms to manipulate the human actin cytoskeleton for survival. So I embarked on studying how Yersinia pestis, one of the deadliest bacteria in human history, perturbs the host actin cytoskeleton to disrupt the process in which host immune cells take up and destroy pathogens. Following on this work, I currently study other disease-causing bacteria to unravel their arsenal of weaponry against the host actin cytoskeleton, and to find alternative methods for treatment of the diseases they cause. When I am not working, I spend time with my daughter who just turned 1 year old! I enjoy travelling, reading and watching science-fiction action-horror films.

 


 

Jantana WONGSANTICHON
jantanaw@imcb.a-star.edu.sg

Jantana's here. Being part of BR lab has given me a great opportunity to do protein structural studies (X-ray crystallography and electron microscopy) and to understand protein (actin and its playmates) dynamics. Outside our working space, I also enjoy a drink or two and sometimes have good badminton challenges with the lab crew.

 


Research Officer


Holiday in Hakone
 

Ke DING
kding@imcb.a-star.edu.sg

I joined BR group in 2010 as a research officer. Prior to that, I worked in a few institutions, including Gene Lab Diagnostic, IMA and GIS A*STAR. I received my BSc in Biology and MSc in Immunology. After work, I enjoy spending time with my family and friends. I also enjoy cooking and traveling.

 


Graduate Students

 

Clément SCIPION
cpmscipion@student.imcb.a-star.edu.sg

Hi I’m Clément!
Before joining the lab, I performed my previous studies in the French ‘Grande école’ école Centrale de Marseille, where I obtained my B. Eng. and M. Eng. Here, my research focuses on actin severing and sequestering peptides that I try to characterize and optimize, in order to understand the mechanisms of these processes.

In my spare time, I enjoy reading, playing badminton, running, listening to Classic Rock and an occasional Blonde Ale. When not organizing a Lab barbecue party to gather former and new lab members and their families together, I love traveling and meeting new people from all over the world. Working in Singapore and especially in Bob’s lab allows me to fulfill this aspiration on a daily basis!

 


 

Lin Jie LEE
ljlee@imcb.a-star.edu.sg

Hi, I’m Lin Jie. I am a AGS (local) phd student and I have been in BR lab since 2009. I am attached to Laurent Blanchoin's lab in France till Sept, I am doing work on the TIRF microscopy and glass surface micro-patterning techniques there. I will be back!

 


 

Eleanor MARTIN
ermartin@student.imcb.a-star.edu.sg

Hi I’m Ellie. I’ve recently joined the group as part of my PhD at the University of Manchester. My research focuses on studying the interaction between the actin cytoskeleton and the chloride ion channel implicated in cystic fibrosis – CFTR.

Before joining the lab, I studied at the University of Bath, and also spent some time studying Mandarin Chinese in Taiwan. In my spare time I enjoy trying to keep up my study of the language, as well as running, cooking, and travelling.

 

 


 

Samson ALI
samsona@student.imcb.a-star.edu.sg

I graduated from the University of Ghana with a BSc (Biochemistry) degree and proceeded to attaining an MSc (Infection and Immunity) from the University of Leeds, UK. Currently pursuing a PhD in the National University of Singapore  and working on characterization of plasmid segregation systems in Prof. Robert Robinson’s Lab.

My leisure is filled with travelling, sightseeing, playing soccer and listening to good music. With determination and in the right lab with necessary expertise as Bob’s, I believe any academic height is attainable!

 


 

Caner AKIL
canera@student.imcb.a-star.edu.sg

Hi, I am Caner,
I obtained my BSc (2011) from University of Caucasian, my MSc (2014) from Izmir Institute of Technology in Turkey. I joined Bob’s laboratory (2015) to elucidate structure and biochemical properties of gelsolin-like and actin-like proteins in different livings.

My favorite acts are riding motorcycles for long distance travel and listening authentic Anatolia music.

 


 

Moses KAKANGA
kakangam@student.imcb.a-star.edu.sg

Working on proteins that come at the extreme end of the central dogma is quite interesting, you get go through all the processes including DNA replication, transcription before you get to your final destination which is translation albeit before post translational modifications.  Working in the BR lab under the mentorship of Prof Robinson has helped me acquire a wealth of knowledge in structural biology.

With a BSc. in Biomedical Sciences and MSc in Structural Molecular Biology this opportunity has availed me a chance to bridge into the realm of deeper science. I am glad to be part of one of the best laboratories in the world and under the mentorship of the coolest boss ever. Join me in my free time as I visit art enclaves the world has to offer.


 

Undergraduate Students

 

Ha LAM
lamdothuyuyenha@gmail.com

Hi I’m Ha Lam!
I am currently an undergraduate, pursuing a degree in Biological Sciences at Nanyang Technological University (NTU). I joined Dr. Robinson’s Lab to understand what the research world entails and also to develop my research interests. Currently, my project here concerns actin interacting protein 1 (aip1).

I like taking slow walks, reading, solving puzzles and playing the piano in my free time. I love exploring, learning from the seniors as well as interacting with people. Therefore, I really enjoy and treasure my time in Dr. Robinson’s lab.
 


Alumni

 

Jennifer LUU (2016)
jenniferluu9@gmail.com

A native of Vancouver, Canada, where she is completing her BSc at the University of British Columbia, Jennifer was a SIPGA intern in Bob’s lab. Her project focused on determining the relationship of the Rab GTPases with the anti-oncogenic drug Apratoxin, in hopes of identifying it as a drug target.  When not singing a love song to convince her bacteria to behave nicely, Jennifer enjoys drawing, running, hiking (she briefly rolled down a mountain once), or having a good time with friends – sometimes with a beer in hand..

 


 

Ciccy WANG (2015)

Hi, I'm Ciccy. I'm currently studying B. Science Adv at the University of Sydney. I came to Bob's lab as a 2 month SIPGA student in my summer holidays to get some research experience. I did a project with Jantana where I attempted to purify and crystallise hot worm actin-binding proteins to determine their structure. I really enjoyed it despite the bacteria being very temperamental with protein expression. I really like travelling so I always try and participate in science projects overseas. In my spare time, I enjoy drawing, reading and gaming (Nintendo DS series). Thanks to the lab for taking me on and helping me!

 


 
Pavithra SINGARAVELU (2015)

Hello, I am Pavithra SINGARAVELU from India. People call me 'Pavi', Easy right? I was a NUS scholar from the Dept. of Biological Sciences (DBS), NUS and I worked in collaboration with Bob's lab for my PhD. I recently graduated in 2015 and now hold a CNRS post-doc position at CEA, Grenoble. I learnt a lot from Bob and other BRians, that has moulded me as a good researcher. Working with BR group was fun and fabulous. I miss everyone and will cherish BR group memories forever.

 


 

Liling WU (2015)

I am Liling and I just graduated this year. I was working in both Ernesto’s and Bob’s labs studying protein methyltransferases over the past four years. It was such a special experience to study and live in Singapore.

 


 

Widyawillis SELAMAT (2015)

Bob was on my thesis advisory committee when I was pursuing my doctorate, and I was always intrigued by his different hairstyles/looks and intelligence each time there was at a meeting. Anyway, I decided to serve my bond with A*STAR from 2012-2015 in his lab because I believed there was plenty that I could learn, and I was not disappointed.  I worked mainly on the actin-binding protein profilin and SILAC-coupled affinity purifications became my forte.

Led by the kindest and most amazing boss ever (no joke!), the BR group was truly fantastic and made science extremely enjoyable. An especially memorable experience indeed, as I ended my stint there with a beautiful addition to my family. Thank you for such great memories!In my free time, I like to travel, running, swimming, listen to calm music and spend my time with my beautiful aquarium.

 


 

Balakrishnan KANNAN (2014)
bala@imcb.a-star.edu.sg

After spending wonderful time in Bob’s lab working on actin-binding proteins, I am now playing with optics and fluorescence! It is awesome to see objects under the different microscopes – with different colours (they are false anyway!) – and all the different interactions!

 


 

David Szatmar (2014)

Hi! I am Dávid (or Daavid)

I was a PhD student in Hungary, Medical School of Pécs, Dept. of Biophysics. Then I spent two fantastic years in Bob's Lab thanks to A*STAR, Research Attachment Program where I got a high level Asian and scientific experience. There I was focused on the dynamical structure of gelsolin. Recently, I returned back to Hungary and we have a collaboration project about MreB characterization. I am glad and my pleasure to know this amazing team of BRers.


 


 

Yong Zi TAN(2014)

Hello, I am Yong Zi! I was a research officer in Bob's lab for a year, working under Jantana to crystallise a series of actin-binding proteins and complexes. I learnt a lot in the lab, and have a lot of fun too! I have continued with my passion for structural biology, and I am now doing my PhD at Columbia University doing single particle electron microscopy.

 


 

Wee Lee CHAN (2014)

Hi, I'm Wee Lee. I was a post-doc in the Robinson lab from January to July 2014 where I worked on Bob's project to understand the structure and function of serine/threonine protein kinase 4 (PAK4).  I also served a secondary function in the lab as Bob's occasional crossword partner. Prior to joining the lab, I went up to St Edmund Hall, Oxford in 2004 to read Biochemistry, after which I did a PhD under Randy Read's supervision at Cambridge.
I am now working on my medical degree at Duke-NUS Medical School, with the hope of becoming a physician-scientist at some point in the distant future. I used to spend my spare time hillwalking, sailing and playing rugby. I also enjoy reading, particularly Graham Greene and Evelyn Waugh.  These days,however, I am happy just to be able to eat three meals, sleep at least five hours a day and pass my exams!

 


 

Mohammad SAIF (2014)

I started my career in structural biology two years back during my masters, which made me realize the beauty of crystallography, how complex systems can be studied in their crystal structures by actually viewing them and modifying them for betterment of human life. After graduating from IIT Bombay, I continued my quest in structural biology and joined Bob's lab as an Intern in a structural collaborative project to study methyl transferase enzymes. Under my mentor Dr. Liling and both of my supervisors Dr. Robert Robinson and Dr. Ernesto Guccione, I learned a lot as a budding crystallography student which build up a solid platform for me to further pave my way to develop successful career. Presently I am working on amyloidogenic proteins trying to investigate their role and their method of fibrillation using different structural techniques.

In my free time, I like to travel, running, swimming, listen to calm music and spend my time with my beautiful aquarium.

 


 

Mårten LARSSON (2013)

Mårten worked with Bob as a Post Doctoral Fellow from 2006 to 2013.

Currently he is back at Uppsala University, Sweden, where he runs a small mass spectrometry-based proteomics facility, connected to the genomics lab of Leif Andersson. There he tries to perform characterization and functional analyses of proteins derived from molecular genomic studies, with the aim to identify associations between genetic variation and phenotype. His life now revolves around his lovely Orbitrap Fusion. Of course he still stays connected to the BR lab, with different collaboration projects. It also gives him a reason to come back and visit Singapore, Music Man, Circle Star and BR lab. In that order. In his spare time Mårten enjoys all kinds of sports. On TV. In the pub.
 


 

Sharon CHEE (2012)

Hi, I am Sharon. I was a research officer working in both Bob’s and Ivana’s groups on a collaboration project to understand the dynamics of gelsolin. I have learnt a lot from Bob and fellow BR lab members and have had lots of fun too! Being in Bob’s lab has sparked my interest in structural biology and I’m currently pursuing that in the p53Lab, working in collaboration with Bob’s group.

In my spare time I enjoy travelling, running, cycling, watching movies, playing pop music on my ukulele and having great company with friends over good food.

 


 

Venkatachalam RAJAKANNAN (2010)
bala@imcb.a-star.edu.sg

Hi I’m Rajakannan, currently an Assistant Professor at the University of Madras and a crystallographer curious on observations. Working 1D [line in the research article] – 2 [to] – 3D [experimental observation], back and forth…
1D-2D-3D ↔ 3D-2D-1D …

 


 

Maria Hernandez-Valladares (2009)

Hi there! I worked in Bob's lab from 2005 to 2009. A lot of protein purification and crystallization! AkTA machines, E. coli and the crystallization robot were my best friends in the lab :)
I work now on MS-based phosphoproteomics in Bergen, Norway. Yes life is a bit different here. It rains 320 days a year so the raincoat and trousers are my second skin.
We enjoy the snow and sleep like bears in winter. We hike and try to sleep during the short nights before the sun arises at 3 am in summer! Never tried to sleep without curtains and with sunglasses? This is the place for that!

I wish you a great success in the present projects and in future funding opportunities!

Hugs from Ernesto and I

 

 


 

Qing MA (2009)

Have great interest in dealing with living things, although my university major was pharmaceutical chemistry. Joining Bob’s team gave me the opportunity to pursue to my true interest. Eager in trying to reveal myth of a few calcium activated actin binding proteins made me forget pay and time passed swiftly…although getting precious protein crystals was the most exciting thing - cloning, protein purification, protein characterization and setting up crystals were also great fun. Still remember that I even tried to hold my breath whiling dealing with extremely calcium sensitive apo-gelsolin. Challenging the limits is the fun of science. After that, I worked about 3 years in the field of science education and developed more communication skills.

Now I am a dedicated mum who is trying to understand early childhood education and to catch up with my young daughter’s Japanese learning speed. Looking forward to do something scientific, educational, and maybe multilingual in the future.  

 


 

Alvin TUNG (2009)

Joined BR lab back in early 2005 when she was still starting up. Really thankful that Bob accepted me into his lab and I spent the next 4 years learning so much about protein purification and crystallization, mastering the art of actin purification, plus an eye opening trip to the Taiwan Synchrotron. Once again thanks to Bob for being such a nice boss and patient mentor, wishing the lab all the best! Alvin is now with the Singapore Police Force doing investigation work.

 


 

Tackey A. Loonchanta (2006)
anantasak@hotmail.com

Hi there, I'm Tackey. I started working with Bob back in year 2003 during my M.Sc. at Uppsala University, Sweden. I had a chance to work at "BR Lab" as a research trainee in 2006, where I was able to quickly get part of my project done and finished my second MSc. from Suranaree University of Technology, Thailand, before Bob sent me on my way to Canada where I graduated with a PhD in Chemistry from The University of British Columbia in 2012.

BR Lab was the fanciest place for Structural Biologist I have ever been in and Bob was my first Protein X-ray Crystallography teacher. My time with Bob, I was working on Gelsolin superfamily proteins along with some of their binding partners for the most part. I always miss my time there.

Settling in Vancouver, Canada, I'm currently starting up my own business while still handling various science projects from time to time.

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