Nicolas PLACHTA 
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  Recent Publications  

Zenker J, White M, Templin R, Parton R, Thorn-Seshold, Bissiere S, Plachta N.
A microtubule organizing center directing intracellular transport in the early mouse embryo.

Zhao Z, White M, Alvarez Y, Zenker J, Bissiere S, Plachta N.
Quantifying transcription factor–DNA binding in single cells in vivo with photoactivatable fluorescence correlation spectroscopy.
Nature Protocols (2017)

White M, Angiolini J, Alvarez Y, Kaur G, Zhao Z, Moksos E, Bruno L, Bissiere S, Levi, Plachta N.
Long-lived binding of Sox2 to DNA predicts cell fate in the four-cell mouse embryo.
Cell  (2016) 
[See Preview by Wu & Ispizua-Belmonte] [Cover image]

Samarage R, White M, Alvarez Y, Fierro-Gonzalez J, Jesudason E, Hanon Y, Fouras A, Plachta N.
Cortical tension positions the first inner cells of the mammalian embryo.
Developmental Cell (2015)
[See Dev Cell Preview by Goldstein & Kiehart, 2015]

Bouveret R et al.
NKX2-5 mutations causative for congenital heart disease retain functionality and are directed to hundreds of targets.
eLife (2015)

Angiolini J, Plachta N, Mocskos E, Levi V.
Exploring the Dynamics of Cell Processes through Simulations of Fluorescence Microscopy Experiments.
Biophysical Journal (2015)

Fierro-Gonzalez J, White M, Silva J, Plachta N.
Cadherin-dependent filopodia control preimplantation embryo compaction.
Nature Cell Biology (2013)
[2 reviews by Faculty 1000]

Kaur G, Nefzger C, Costa M, Silva J, Fierro-Gonzalez J, Polo J, Bell T, Plachta N.
Probing transcription factor diffusion in the developing mammalian embryo with photoactivatable fluorescence correlation spectroscopy.
Nature Communications (2013)

Plachta N, Bollenbach T, Pease S, Fraser SE, Pantazis P.
Oct4 kinetics predict cell lineage patterning in the early mammalian embryo.
Nature Cell Biology (2011)
[Journal Cover. See NCB News & Views by Zernicka-Goetz, 2011. 3 reviews by Faculty 1000.]

Bissiere S, Plachta N, McAllister K, Hoyer D, Olpe HR, Grace A, Cryan JF.
The anterior cingulate cortex modulates the efficiency of amygdala dependent fear learning.
Biological Psychiatry (2008) (Journal Cover)

Nikoletopoulou V, Plachta N, Allen ND, Haubst N, Götz M, Barde Y-A.
Neurotrophin receptor-mediated death of misspecified neurons generated from embryonic stem cells lacking Pax6.
Cell Stem Cell (2007)

Plachta N, Annaheim C, Bissiere S, Hoving S, Voshol V, Bibel M, Barde Y-A.
Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells.
Nature Neuroscience (2007)

Plachta N, Bibel M, Tucker KL, Barde Y-A.
Developmental potential of defined neural progenitors derived from mouse embryonic stem cells.
Development (2004)

Plachta N, Traister A, Weil M.
Nitric oxide is involved in establishing the balance between cell cycle progression and cell death in the developing neural tube.
Experimental Cell Research (2003)

Traister A, Abashidze S, Gold V, Michael E, Plachta N, Patel K, Fainsod A, Weil M.
BMP controls nitric oxide-mediated regulation of cell numbers in the neural tube.
Cell Death and Differentiation (2004)

Traister A, Abashidze S, Gold V, Plachta N, Karchovsky E, Patel K, Weil M.
Evidence that nitric oxide regulates cell cycle progression in the developing chick neuroepithelium.
Developmental Dynamics (2002)


Plachta N.
New embryo users.
Cell  (2017)

White M, Zenker J, Bissiere S, Plachta N.
How cells chose their shape and position in the early mouse embryo.
Current Opinion in Cell Biology  (2016)

Zhao Z, White MD, Bissiere S, Levi V, Plachta N.
Quantitative imaging of mammalian nuclear dynamics: From single cells to whole embryos.
BMC Biology  (2016)

White M, Bissiere S, Plachta N.
Mouse embryo compaction.
Current Topics Developmental Biology  (2016)

White M, Plachta N.
How adhesion forms the early mammalian embryo.
Current Topics Developmental Biology (Review, 2005)

White M, Plachta N.
The first cell fate decision during mammalian development
Stem Cells, Tissue Engineering & Regenerative Medicine
Imperial College Press (Book Chapter, 2005)

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