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  current news   Press        
     
 
  9 December 2016
 

Cyclin A2 regulates erythrocyte morphology and numbers


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  6 December 2016
 

Structural basis for specific recognition of pre-snRNA by Gemin5


Full Story



  29 November 2016
 

Activation of mutant TERT promoter by RAS-ERK signalling is a key step in malignant progression of BRAF-mutant human melanomas


Full Story



  22 November 2016
 

Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors


Full Story



  18 November 2016
 

Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression


Full Story



  31 October 2016
 

Human Stem Cell-Derived Endothelial-Hepatic Platform for Efficacy Testing of Vascular-Protective Metabolites From Nutraceuticals


Full Story



  18 October 2016
 

Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation


Full Story



  12 October 2016
 

Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint


Full Story



  5 October 2016
 

Cdk2 catalytic activity is essential for meiotic cell division in vivo


Full Story



  27 September 2016
 

Long-range chromatin interactions drive mutant Tert promoter activation

Full Story


  20 September 2016
 

Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression

Full Story


  14 September 2016
 

The genome of the largest bony fish, ocean sunfish (Mola mola), provides insights into its fast growth rate

Full Story


  7 September 2016
 

Proline isomerisation as a novel regulatory mechanism for p38MAPK activation and functions

Full Story


  22nd August 2016
 

Single-cell multimodal profiling reveals cellular epigenetic heterogeneity

Full Story


  15th August 2016
 

Two-Step Forward Genetic Screen in Mice Identifies Ral GTPase-Activating Proteins as Suppressors of Hepatocellular Carcinoma

Full Story


  5th August 2016
 

Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq

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  22nd July 2016
 

Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus

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  8th July 2016
 

Structural basis for blocking PD-1 mediated immune response by therapeutic antibody pembrolizumab

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  27th June 2016
 

Proximity biotinylation provides insight into the molecular composition of focal adhesions at the nanometer scale

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  17th June 2016
 

PRL3-zumab, A First-in-Class Humanized Antibody for Cancer Therapy

Full Story