Jean Paul THIERY    
                       
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  Publications  
 

Mechanochemistry of cell adhesion

Théry M, Jiménez-Dalmaroni A, Racine V, Bornens M, Jülicher F.
Experimental and theoretical study of mitotic spindle orientation.
Nature. 447:493-6, 2007.

Cuvelier D, Théry M, Chu YS, Dufour S, Thiéry JP, Bornens M, Nassoy P, Mahadevan L
The universal dynamics of cell spreading,
Current Biology, 17:1-6, 2007.
 
Chu YS, Eder O, Thomas WA, Simcha I, Pincet F, Ben-Ze’ev A, Perez E, Thiery JP, Dufour S
Prototypical Type-I E-cadherin and Type-II cadherin-7 mediate very distinct adhesiveness through their extracellular domain. J. Biol. Chem. 281:2901-10, 2006.

Théry M, Racine V, Pépin A, Piel M, Chen Y, Sibarita JB, Bornens M.
The extracellular matrix guides the orientation of the cell division axis.
Nat Cell Biol. 7:947-53, 2005.

Chu YS, Dufour S, Thiery JP, Perez E, Pincet F
Johnson-Kendall-Roberts theory applied to living cells.
Phys. Rev. Lett. 94:028102, 2005

Chu YS, Thomas WA, Eder O, Pincet F, Perez E, Thiery JP, Dufour S
Force measurements in E-cadherin-mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through Rac and Cdc42.
J. Cell Biol. 167:1183-94, 2004

Epithelial mesenchymal Transition

J.P. Thiery and J. Sleeman.
Complex networks orchestrate epithelial-mesenchymaltransitions.
Nat. Rev. Mol. Cell Biol. 7 : 131-142, 2006.

Breast cancer oncogenomics

Bollet MA, Servant N, Neuvial P, Decraene C, Lebigot I, Meyniel JP, De Rycke Y, Savignoni A, Rigaill G, Hupé P, Fourquet A, Sigal-Zafrani B, Barillot E, Thiery JP.
High-resolution mapping of DNA breakpoints to define true recurrences among ipsilateral breast cancers.
J Natl Cancer Inst.
100:48-58, 2008.

Stransky N, Vallot C, Reyal F, Bernard-Pierrot I, de Medina SG, Segraves R, de Rycke Y, Elvin P, Cassidy A, Spraggon C, Graham A, Southgate J, Asselain B, Allory Y, Abbou CC, Albertson DG, Thiery JP, Chopin DK, Pinkel D, Radvanyi F.
Regional copy number-independent deregulation of transcription in cancer.
Nat Genet.
38:1386-96, 2006.

Breast cancer micrometastases

Vincent-Salomon A., Pierga J.Y., Couturier J., d’Enghien C.D.,  Nos C., Sigal-Zafrani B., Lae M., Freneaux P., Dieras V., Thiery J.P. and  Sastre-Garau X.
HER2 status of bone marrow micrometastasis and their corresponding primary tumours in a pilot study of 27 cases; a possible tool  for anti HER2 therapy management?
Br. J. Cancer 96: 654-659, 2007.

Braun S., Vogl F., Naume B., Janni W., Osborne M. P., Coombes R. C., Schlimok G, Diel I. J., Gerber B., Gebauer G, Pierga.J-Y., Marth C, Oruzio D., Wiedswang G, Solomayer, E-F., Kundt G., Strobl B., Fehm T., Wong G. Y. C., Bliss J., Vincent-Salomon A., and Pantel, K. for the Pooled Analysis Study
Pooled Analysis Study Group (additional contributors) : Wischnik A., Mueller P., Steinfeld D., Schulz C., Borgen E, Kåresen R, Nesland J M., Kvalheim G., Friese K., Krause A., Sommer H. L., Rack B., Jaeger W., Potter C., Mansi J. L., Homewood J., Magdalénat H., J-P. Thiery.
International Pooled Analysis of Prognostic Significance of Bone Marrow Micrometastasis in Patients with Stage I, II, or III Breast Cancer.
New England  J. Med. 353:793-802, 2005.

Neural crest cells

M. Breau, M. Eder, O. Blanche, C. Brakebush, R. Fassler, J.P. Thiery and S. Dufour.
Removal of b1 integrin in the enteric neural crest lead to a Hirschprung disease
Development 133: 1725-1734, 2006.

Broders-Bondon F.,  Cheneau A., Romero-Oliva F.,  Mayor R Mazabraud A. and Thiery JP.
Regulation of Xsnail2 expression by RhoGTPases.
Dev. Dyn. 236: 2555-2566, 2007.

Modeling breast cancer basal phenotype

J. Teulière, M.M. Faraldo, M-A. Deugnier, M. Shtutman, A. Ben Ze’ev, J.P. Thiery and M.A. Glukhova 
Targeted activation of beta-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia.
Development 132: 267-277, 2005.


Imaging  in cell biology

Moutsimilli L, Farley S, El Khoury MA, Chamot C, Sibarita JB, Racine V, El Mestikawy S, Mathieu F, Dumas S, Giros B, Tzavara ET.
Antipsychotics increase vesicular glutamate transporter 2 (VGLUT2) expression in thalamolimbic pathways. Neuropharmacology, 2007.

Racine V, Sachse M, Salamero J, Fraisier V, Trubuil A, Sibarita JB.
Visualization and quantification of vesicle trafficking on a three-dimensional cytoskeleton network in living cells.
J Microsc. 225:214-28, 2007.

Bioengineering

Chua KN, Lim WS, Zhang P, Lu H, Wen J, Ramakrishna S, Leong KW, Mao HQ.
Stable immobilization of rat hepatocyte spheroids on galactosylated nanofiber scaffold.
Biomaterials
26:2537-2547, 2005.

Lu HF, Chua KN, Zhang PC, Lim WS, Ramakrishna S, Leong KW, Mao HQ.
Three-dimensional co-culture of rat hepatocyte spheroids and NIH/3T3 fibroblasts enhances hepatocyte functional maintenance.
Acta Biomaterialia 1:399-410, 2005.

Emma Luong-Van ,  Lisbeth Grøndahl ,  Kian Ngiap Chua ,  Kam W Leong ,  Victor Nurcombe ,  Simon M Cool
Controlled release of heparin from poly(epsilon-caprolactone) electrospun fibers.
Biomaterials 27:2042-2050, 2006.

Kian-Ngiap Chua, b, Chou Chai, Peng-Chou Lee, Yen-Ni Tang, Seeram Ramakrishna, Kam W. Leong and Hai-Quan Mao
Surface-aminated electrospun nanofibers enhance adhesion and expansion of human umbilical cord blood hematopoietic stem/progenitor cells.
Biomaterials 27:6043-6051, 2006.

Kian-Ngiap Chua, Yen-Ni Tang, Chai-Hoon Quek, Seeram Ramakrishna, Kam W. Leong and Hai-Quan Mao
Dual-functional fibrous scaffold enhances P450 activity of cultured primary rat hepatocytes.
Acta Biomaterialia
3:643-650, 2007.

K. Chua, C. Chai, P. Lee, S. Ramakrishna, K. Leong, H. Mao
Functional nanofiber scaffolds with different spacers modulate adhesion and expansion of cryopreserved umbilical cord blood hematopoietic stem/progenitor cells.
Experimental Hematology 35:771-781, 2007.

Kenneth Lin, Kian-Ngiap Chua, Gregory T. Christopherson, Shawn Lim and Hai-Quan Mao
Reducing electrospun nanofiber diameter and variability using cationic amphiphiles.
Polymer 48:6384-6394, 2007.

 
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