Bioinformatician position

Date available: immediately

Date posted: 18 March, 2013

A Postdoctoral Bioinformatician position is available immediately at the IMCB Epigenetics and Cell Fates Laboratory. The laboratory is interested in dissecting the genetic and epigenetic mechanisms regulating cell fate changes, while developing novel tools and strategies in deriving differentiated cell types via defined factors reprogramming.

Applicants with a strong background in Bioinformatics and next-generation sequencing data analysis are invited to apply. Successful candidates must be highly motivated, have passion for research and be able to work in an interdisciplinary environment.

- Ph.D. from a well-recognized institution with a strong research background in Bioinformatics  
  /Computer science/Biostatistics or equivalent
- Experience in bioinformatics and data analysis for DNA microarray, ChIP-seq and RNA-seq
- Experience with open source bioinformatics tools
- Excellent analytical, technical and problem solving skills
- Knowledge with biostatistics highly desirable
- Self-starter who is comfortable working in a fast moving interdisciplinary team
- Strong publication record in peer-reviewed journals
- Committed and able to work flexible hours
- Excellent communication, technical writing and presentation skills

Interested candidates are asked to send a cover letter detailing research motivation, CV, and the names and email addresses of three references to Jonathan Loh (yhloh@imcb.a-star.edu.sg). Applicants can visit the lab website to find out more (http://www.imcb.a-star.edu.sg/php/jl.php).

References:

1) Gore A et al.
    Somatic coding mutations in human induced pluripotent stem cells. (2011)
    Nature 471, 63-67.
2) Agarwal S et al.
    Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients.     (2010)
     Nature 464, 292-296.
3) Loh YH et al.
    The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem     cells. (2006)
    Nature Genetics 38, 431–440.

Project Manager - Slide Scanning and Image Analysis

(Ref: BMSI/IMCB/AMPL/25012013)

Date available: immediately

Date posted: 15 Feb, 2013

The Advanced Molecular Pathology Laboratory (AMPL) at IMCB invites applications for the post of Project Manager to lead the Imaging and Analysis unit in this dynamic core histopathology facility.

The laboratory provides support to the research community in Singapore, specializing in research histopathology. The laboratory prides itself on providing the highest quality, leading edge capabilities, of which imaging and image analysis of biological specimens is a key component.

- MSc. Or Ph.D. in a field relevant or applicable to biological imaging and image analysis is   preferred, other areas of expertise will be considered.
- Good background knowledge of microscopy
- Strong analytical skills, especially in the area of image processing and analysis applications
- A strong background in biology or biological sciences is essential
- Programming and algorithm development skills would be an advantage

We are looking for a candidate who can work independently on projects as the project leader but also be part of a larger team. Good interpersonal and organizational skills are essential, with the ability to interact with senior scientists from research and industry. The successful applicant will be expected to write reports and prepare regular project updates, ensuring the project meets pre-established objectives and timelines.

Interested applicants are welcome to fax or write in with a detailed resume, supporting documents and contact numbers to: Human Resources Department, Institute of Molecular and Cell Biology, 61 Biopolis Drive, Level 2, #02-03, Proteos Building, Singapore 138673; Fax: 6779 1117 or email to: recruit@imcb.a-star.edu.sg.

Histology Laboratory Manager

Date available: immediately

Date posted: 15 Feb, 2013

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences funded by the Agency for Science, Technology and Research (A*STAR). Its mission is to develop and foster a vibrant research culture for cutting-edge basic biomedical sciences. IMCB’s research activities focus on the areas of Animal Models of Development and Disease, Cancer Genetics and Therapeutics, Cell Biology in Health and Disease, and Structural Biology and Drug Discovery. IMCB is continuously looking out for talented people to contribute to its success. We are now inviting suitable candidates to apply for the following position:

Histology Laboratory Manager
(Ref: BMSI/IMCB/Histo/LM/05022013)

Responsibilities:

The IMCB Histopathology Laboratory is a state of the art core service facility serving the entire research community in Singapore. The successful candidate will responsible for the overall day-to-day administration of the laboratory in areas of staffing, institutional health and safety regulations, operational requirements etc. He/She will also be required to oversees the quality control programme for the laboratory and ensure that customer needs are met at all times.

- Possess at least a diploma in Biomedical Sciences or Equivalent
- Must have at least 5 years full time experience in a research histology laboratory working with   animal tissues from multiple species.
- Should have a minimum of 5 years experience working in a GLP laboratory or a similar accredited   environment
- Willing and able to work with laboratory animals, including rodents, lagomorphs, non-human   primates, pigs etc.

IInterested applicants are welcome to fax or write in with a detailed resume, supporting documents and contact numbers to: Human Resources Department, Institute of Molecular and Cell Biology, 61 Biopolis Drive, Level 2, #02-03, Proteos, Singapore 138673; Fax: 6779 1117 or email: recruit@imcb.a-star.edu.sg.

We regret that only shortlisted applicants will be notified.