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  Principal Investigators   IMCB JUNIOR Investigators   IMCB Independent Fellow   research fellows   research/Lab Officers   OTHER Opportunities    
     
 


Research Fellow Position

Date available: Immediate

Date posted: 31 October 2014

A postdoctoral position is available in the laboratory of Dr. Vinay Tergaonkar at the Institute of Molecular and Cell Biology (IMCB), Singapore.
Reference: http://www.imcb.a-star.edu.sg/php/vinayt.php

Requirements:
    • Ph.D in Molecular biology and bioinformatics or related fields
    • At least one first author publication in a reputable international journal along with enthusiasm and active interest in pursuing research in the areas of genomics, cancer and metabolism.
    • Experience in computational genomics (e.g. next-generation sequencing analysis)
    • Python, Perl, C, C++, Java, R, or other related programming knowledge, with a strong quantitative, statistics and bioinformatics background
    • Ability to work on Linux environment (familiar with bash/shell commands), and to perform multi-threaded programs
    • Help to analyze next-generation sequencing data, design experiments, write papers, and compete for fellowships.
    Interested candidates are to email a detailed CV that includes research motivation and publication list to vinayt@imcb.a-star.edu.sg or recruit@imcb.a-star.edu.sg

    The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice.

    We regret that only shortlisted applicants will be notified.





Research Fellow Position: Humanised Mouse Unit, IMCB

Date available: Immediate

Date posted: 29 September 2014

One Research Fellow (Postdoctoral) position is immediately available in the Humanized Mouse Unit (HMU) of Institute of Molecular and Cell Biology, A*STAR, Singapore.

Our laboratory studies human infectious diseases and cancers using a combination of biochemical, molecular and immunological approaches in human-mouse chimera models. For a research overview, please refer to our website: http://www.imcb.a-star.edu.sg/php/ittd-hmu.php

Qualifications/Requirements

The candidate should:

  • be self-driven to pursue a scientific career, motivated, independent and passionate about immunology research.
  • hold a doctoral degree in a relevant field of immunology, virology or oncology.
  • have a good knowledge and concept of immunology with demonstrated research experience and achievement.
  • have good technical writing skills for international peer-reviewed journals.
  • have prior experience in working with mice, flow cytometry, immunofluorescence etc.

Responsibilities

  • Undertake independent research under the direction of the PI and with other lab members.
  • Assist the PI in quality control for experiments, data analysis, manuscript preparation, grant applications and  lab management.
  • Assist the PI in guiding and training students and junior research staff.
  • Present research achievements at internal and external seminars and conferences.

Please email a detailed CV containing a list of publications to
Dr. Qingfeng Chen, qchen@imcb.a-star.edu.sg

or to
Human Resources Department, Institute of Molecular and Cell Biology, 61 Biopolis Drive, Level 2, #02-02, Proteos Building, Singapore 138673; Fax: 6779 1117 or email to : recruit@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.





Positions in Next-Generation sequencing @ IMCB

Date available: Immediate

Date posted: 26 August 2014

Description:

The Institute of Molecular and Cell Biology (IMCB) is currently looking for a Research Scientist/ Fellow/ Officer (Next-Generation sequencing/wet lab) and a Research Fellow/ Officer (Bioinformatician).

1. Research Scientist/ Fellow/ Officer (Next-Generation sequencing/wet lab)

The successful candidate will play an essential role in research and development within IMCB, interacting with multiple scientists, and enabling the use of the NGS platform. He/She will be part of a highly motivated team of scientists and technicians, but is expected to work independently.

Responsibilities will include the preparation, development and optimization of genome- and transcriptome-sequencing (Next-Generation sequencing) libraries and protocols; managing and coordinating collaborations with research groups, participating in experimental design and contributing to final written reports.

Requirements:

  • Master or PhD degree in Biomedical Sciences.
  • Five years or more work experience in a molecular biology lab.
  • Experience with next-gen sequencing is preferred.
  • Familiarity with DNA sequencing, Primer-design softwares.

2. Research Fellow/ Officer (Bioinformatician)

The successful candidate will work in a dynamic multi-disciplinary team and collaborate with other bioinformaticians and biologists in supporting NGS research projects.

Responsibilities will include running pipelines for extracting and analyzing massive parallel sequencing data from Next Generation Sequencers; curate and integrating in-house genomic (ChIP-seq, DNA-seq, exon-seq, RNA-seq et al.) data sets.

Requirements:

  • Master or PhD Degree in Bioinformatics, Computer Science, or related disciplines.
  • Work experience in a computational or molecular biology lab.
  • Background in scripting languages, Perl/python, SQL, and Unix programming is essential.
  • Good working knowledge and experience in data management for genomic (ChIP-seq, DNA-seq, RNA-seq et al.) will be an advantage.

Interested applicants should send a CV and a brief description of research experience to:
Dr. Ernesto 
GUCCIONE
eguccione@imcb.a-star.edu.sg

or to
Human Resources Department, Institute of Molecular and Cell Biology, 61 Biopolis Drive, Level 2, #02-02, Proteos Building, Singapore 138673; Fax: 6779 1117 or email to :
recruit@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.



Postdoctoral fellow position

Date available: Immediate

Date posted: 24 July 2014

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences funded by the Agency for Science, Technology and Research (A*STAR). Its vision is to be a premier molecular biology and cell institute with increasing focus on addressing the mechanistic basis of human diseases. IMCB’s research activities focus on the areas of Animal Models of Development and Disease, Cancer Genetics and Therapeutics, Cell Biology in Health and Disease, and Structural Biology and Drug Discovery. IMCB is continuously looking out for talented people to contribute to its success.

Research Fellow

A postdoctoral research fellow position is immediately available for the PRL-3 Phosphatase & Cancer lab at IMCB. The successful applicant will be involved in an A*STAR project and is required to work closely with fellow team members from Dr Zeng’s laboratory. 

The successful candidate must be stimulated by interdisciplinary discussions and be motivated to develop and carry out strategies that assess outcomes of specific mission-oriented research.

Requirements:

  • PhD (or MD-PhD preferred) in Biology.
  • Self-motivated, with experience in animal cancer models and histology.
  • Demonstrated research experience in protein work, molecular cloning and cell culture.
  • Strong publication record in peer-reviewed journals.
  • Ability to work in a team and conduct independent research with excellent analytical, technical and problem solving skills.
  • Ability to present research progress at internal and external seminars/conferences.

Interested candidates are to email a detailed CV that includes research motivation and publication list to: Human Resources Department, Institute of Molecular and Cell Biology, 61 Biopolis Drive, Level 2, #02-02, Proteos Building, Singapore 138673; Fax: 6779 1117 or email to : recruit@imcb.a-star.edu.sg or mcbzengq@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.





Postdoctoral fellow position

Date available: Immediate

Date posted: 9 July 2014

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences funded by the Agency for Science, Technology and Research (A*STAR). Its vision is to be a premier molecular biology and cell institute with increasing focus on addressing the mechanistic basis of human diseases. IMCB’s research activities focus on the areas of Animal Models of Development and Disease, Cancer Genetics and Therapeutics, Cell Biology in Health and Disease, and Structural Biology and Drug Discovery. IMCB is continuously looking out for talented people to contribute to its success.

Research Fellow (Job Ref: BMSI/IMCB/ZTU/RF/17042014)

A postdoctoral research fellow position is immediately available for 6 months at the Zebrafish Translational Unit in IMCB. The successful applicant will be involved in an A*STAR MINDEF project and is required to work closely with fellow team members from DSO laboratory. 

The successful candidate must be stimulated by interdisciplinary discussions and be motivated to develop and carry out strategies that assess outcomes of specific mission-oriented research.

Qualification/Requirements

  • PhD in Biological Sciences or relevant fields.
  • Knowledge of fish husbandry.
  • Experience in electrophysiology and bio-imaging.
  • Strong publication record in peer-reviewed journals.
  • Ability to work in a team and conduct independent research with excellent analytical, technical and problem solving skills.
  • Ability to present research progress at internal and external seminars/conferences.

Interested candidates are to email a detailed CV that includes research motivations, publication list to: Human Resources Department, Institute of Molecular and Cell Biology, 61 Biopolis Drive, Level 2, #02-02, Proteos Building, Singapore 138673; Fax: 6779 1117 or email to : recruit@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.





Postdoctoral fellow position

Date available: Immediate

Date posted: 8 July 2014

Research Fellow in the Laboratory of Asst Prof Wang Xiaomeng, LKCMedicine, NTU and Laboratory of Prof Hong Wanjin, IMCB, A*STAR

Lee Kong Chian School of Medicine (LKCMedicine) is a new joint medical school by Imperial College London and Nanyang Technological University, Singapore. It was established in September 2010 and will operate from two campuses – Yunnan Campus at Nanyang Technological University and a new campus to be built at Novena. Its primary healthcare partner is the National Healthcare Group (NHG) which comprises an integrated network of primary healthcare polyclinics, acute care hospitals such as Tan Tock Seng Hospital, and national specialty centres. Lee Kong Chian School of Medicine will deliver a new five-year undergraduate medical programme resulting in a joint degree (MBBS) awarded by Imperial College London and Nanyang Technological University. The first cohort of 50 students has started in August 2013.

The Institute of Molecular and Cell Biology (IMCB) was launched in 1985 to develop and support biomedical R&D capabilities in Singapore. Its original vision was to foster a vibrant research culture to enable cutting edge discoveries and nurture high-quality talent. Today, IMCB has established itself as a premier molecular & cell biology institute, addressing the mechanistic basis of human diseases. IMCB Discovery research includes Cell Biology in Health and Disease; Animal Models of Development & Disease; Cancer & Stem Cell Genetics & Genomics; and Structural Biology & Drug Discovery. IMCB Translational research includes Humanized Model Organisms for Human Diseases; Systems Approach for Disease Target Identification & Validation; and Protein Engineering & Antibody Development for Diagnostics & Therapeutics. Research in IMCB is supported by cutting edge infrastructure and facilities including Quantitative Proteomics; Humanized Mice; Mouse Models of Human Cancer; Protein Crystallography X-Ray; Zebrafish for Drug Metabolism & Toxicology; Advanced Molecular Histopathology; Imaging & Electron Microscopy; DNA Sequencing; Medicinal Chemistry & Drug Development; Genome-wide RNAi screens; and Monoclonal Antibody.

We are currently recruiting a Research Fellow who will be working closely with Dr Wang Xiaomeng, Assistant Professor at LKCMedicine/Joint Principal Investigator at IMCB and Prof Hong Wanjin, Executive Director, IMCB.

The appointed Research Fellow will be involved in studying the TGFβ mediated angiogenesis using the state-of-art in vitro, ex vivo and in vivo technologies. The ultimate goal is to develop novel treatment strategies

This Research Fellow will have the opportunity to work in a dynamic environment with experienced molecular and cell biologists, and geneticists. The appointed Research Fellow will also have access to leading edge core facilities.

Qualification/Requirements

1. The successful candidate must have a MD-PhD or a PhD with a good knowledge of TGFβ      signaling and Vascular Biology.
2.  The candidate must be skilled in biochemical, molecular and cell biology analysis.
3.  The candidate must have experience with cell and organ culture. Previous experience in      adenovirus preparation would be ideal.
4.  The candidate should be able to carry out independent research with minimal supervision.
5.  The candidate should have excellent interpersonal, oral and written communication skills.
6.  Previous publications in international peer reviewed journals are a prerequisite.

Application Procedure:
Please send in applications to Dr Andrew Ang, Director, Research Administration and Support Services (email: angdrewang@ntu.edu.sg) or recruit@imcb.a-star.edu.sg with your CV, list of publications, statement of research interests and names of three references at your earliest convenience. For further queries, you may write to Dr. Xiaomeng Wang (email: wangxiaomeng@ntu.edu.sg) and Prof Wanjin Hong (email: mcbhwj@imcb.a-star.edu.sg).

Only shortlisted candidates will be notified.





Postdoctoral Research Fellow Position

Date available: Immediate

Date posted: 8 July 2014

One Research Fellow (postdoctoral) position is immediately available in the Humanized Mouse Unit (HMU) of the Institute of Molecular and Cell Biology, A*STAR, Singapore.

Our laboratory studies human infectious diseases and cancers using a combination of biochemical, molecular and immunological approaches in human-mouse chimera models. Our research is a fast-developing area in biomedical and bioengineering science, which is critical to the understanding and development of therapeutics for many human specific diseases. Research overview (Website: http://www.imcb.a-star.edu.sg/php/ittd-hmu.php)

Qualification/Requirements

  • The candidate should be self-driven to pursue a scientific career, motivated, independent and passionate about immunology research

  • Hold a doctoral degree or be in the final stage of completing doctoral study in a relevant field of immunology or virology

  • Good knowledge and concept of immunology and demonstrated research experience and achievement

  • Good technical writing skills

  • Prior experience in working with mice, flow cytometry, immunofluorescence etc

Requirements:

  • Undertake independent research under the direction of the Group Leader and with other lab members
  • Assist the Group Leader in quality control for experiments, data analysis, manuscript preparation, grant applications and lab management
  • Assist the Group Leader in guiding and training students and research staff
  • Present research achievements at internal and external seminars and conferences

Please email a detailed CV containing a list of publications and the names of 3 referees to
Dr. Qingfeng Chen, qchen@imcb.a-star.edu.sg  or  recruit@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.


Postdoctoral research fellow position

Date available: Immediate

Date posted: 3 June, 2014

A Postdoctoral research fellow position is available immediately at the IMCB Epigenetics and Cell fates Laboratory. The laboratory is interested in developing novel tools and strategies in deriving differentiated cell types via defined factors reprogramming.

Applicants with relevant background in Stem cell biology, Haematology, Neurobiolgy or related fields are invited to apply. Experience with Human ESCs differentiation and mouse work would be highly desirable. Successful candidates must be highly motivated, have passion for research and be able to work in an interdisciplinary environment.

Requirements:

  • Ph.D. from a well-recognized institution in Stem cell biology/Life Sciences/Biomedical Sciences
  • Strong publication record in peer-reviewed journals
  • Committed and able to work flexible hours
  • Ability to conduct high-quality independent research with excellent analytical, technical and problem solving skills.
  • Excellent communication, technical writing and presentation skills

Interested candidates are asked to send a cover letter detailing research motivations, CV, and the names and email addresses of three references to Jonathan Loh (yhloh@imcb.a-star.edu.sg). Applicants can visit the lab website to find out more (http://www.imcb.a-star.edu.sg/php/jl.php).

We regret that only shortlisted applicants will be notified.

References:

  1. Gore A et al. Somatic coding mutations in human induced pluripotent stem cells. (2011)
    Nature 471, 63-67.
  2. Agarwal S et al. Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients. (2010) Nature 464, 292-296.
  3. Loh YH et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. (2006) Nature Genetics 38, 431–440.





Research Fellow - Proteomics

Date available: September 2014

Date posted: 30 May, 2014

A Research Fellow position in Mass Spectrometry (MS)-based proteomics under the Institute of Molecular and Cell Biology-Singapore Eye Research Institute (IMCB-SERI) Joint Programme in Retinal Angiogenic Diseases is available for highly motivated candidates. The successful candidate will be responsible for protein biomarker discovery in biofluids using advanced MS technology (both discovery and targeted). The successful candidate will join a multidisciplinary team and be assisted by junior staff.

Requirements:

Candidates with a Ph.D in Biochemistry/Analytical Chemistry or related areas are invited to apply. Prior postdoctoral training in the field of proteomics (2-6 years) or proven track record in proteomics research is preferred. The applicant should be familiar with MS-based proteomic pipeline including sample preparation, high resolution MS operation and data analysis. Experience in molecular biology and familiarity with downstream bioinformatics processing will be an advantage. The successful candidate should be capable of executing independent research and also perform well in a team.

Interested applicants should email his/her curriculum vitae, brief statement of research summary/prior experience and contact information of at least two references to Dr. Jayantha Gunaratne (jayanthag@imcb.a-star.edu.sg).

We regret that only shortlisted candidates will be contacted.



Postdoctoral Research Fellow Position

Date available: Immediate

Date posted: 5 May, 2014

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences funded by the Agency for Science, Technology and Research (A*STAR). Its mission is to develop and foster a vibrant research culture for cutting-edge basic biomedical sciences. IMCB’s research activities focus on four major fields: Animal Models of Development and Disease, Cancer Genetics and Therapeutics, Cell Biology in Health and Disease, and Structural Biology and Drug Discovery. IMCB is continuously looking out for talented people.

The Monoclonal Antibody Unit (MAU) in IMCB aims to generate and characterize monoclonal antibodies that are useful for translational research.  We are also involved in virus research. We are now inviting suitable candidates to apply for the following position as part of a Joint Council Office Development Programme entitled “Establishment of a humanized mouse model for study of bona fide hepatitis virus infection, immune responses and drug development”.

Research Fellow

Responsibilities:

  • Contribute actively to the above programme by taking charge of the virology aspects including studying the infection of hepatitis B and C viruses in the humanized mouse model.

  • Perform molecular biology and biochemistry experiments such as cell culture, cloning, protein expression and purification, Western blot and immunofluorescence analyses.

  • Generation and characterization of monoclonal antibodies for therapeutic and diagnostic applications.

Requirements:

  • Prospective candidates should possess a Ph.D. in relevant fields such as virology or immunology.
  • Experience with animal handling, protein expression, microscopy imaging and immunological techniques is preferred.
  • Possess excellent academic records and technical skills, strong publication record in reputable international journals.
  • • A team player with good communication skills.

IInterested applicants are welcome to fax or write in with a detailed resume, supporting documents and contact numbers by to: Human Resources Department, Institute of Molecular and Cell Biology, 61 Biopolis Drive, Level 2, #02-02, Proteos Building, Singapore 138673; Fax: 6779 1117 or email to : recruit@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.


Postdoctoral Research Fellow Position

Date available: Immediate

Date posted: 8 April, 2014

A postdoctoral research fellow position is immediately available at the Zebrafish Translational Unit in IMCB. The successful applicant will be involved in an A*STAR JCO funded project and is required to work closely with fellow team members from IMRE. 
The ideal candidate should hold a Ph.D. in molecular biology, developmental biology, biochemistry or other relevant fields. Experience in working with zebrafish, developing disease models and bioimaging is desired. The successful candidate must be stimulated by interdisciplinary discussions and be motivated to develop and carry out strategies that assess outcomes of specific mission oriented research.

Examples of published research conducted by the Zebrafish Translational Unit in IMCB highlighting the varied approaches used to validate performance of novel fabricated nanomaterials are listed in references below.

References:

  1. You WH, Teh C, Tan H, Wong S-Y, Zhang Y, Korzh V, Li X, Wang J: PEO surface-decorated silica nanocapsules and their application in in vivo imaging of zebrafish RSC Adv 2012(2):12392-12399.
  2. Yan H, Teh C, Sreejith S, Zhu L, Kwok A, Fang W, Ma X, Nguyen KT, Korzh V, Zhao Y: Functional mesoporous silica nanoparticles for photothermal-controlled drug delivery in vivo. Angew Chem Int Ed Engl 2012, 51(33):8373-8377.
  3. Ma X, Teh C, Zhang Q, Borah P, Choong C, Korzh V, Zhao Y: Redox-Responsive Mesoporous Silica Nanoparticles: A Physiologically Sensitive Codelivery Vehicle for siRNA and Doxorubicin. Antioxid Redox Signal 2013.

Requirements:

  • Ph.D. from a well-recognized institution in Life Sciences/Biomedical Sciences.
  • Strong publication record in peer-reviewed journals.
  • The ability to work in a team and conduct independent research with excellent analytical, technical and problem solving skills.
  • Ability to present research progress at internal and external seminars/conferences.

Interested candidates are to email a detailed CV that includes research motivations, publication list and email address of at least 3 referees to Cathleen Teh (cathleen@imcb.a-star.edu.sg).

We regret that only shortlisted applicants will be notified.