jobs
 
 
Living in Singapore


SINGAPORE INFOMAP
The Singapore Infomap (www.sg) is your first stop portal to Singapore, with links to general Singapore facts and resources, latest news and events.

CONTACT SINGAPORE
Includes a job bulletin board, employers' profiles, and other information and services to assist Singaporeans abroad and foreigners.

SINGAPORE EXPATS
Singapore Expats - Guide on expat relocation, Singapore property rental, Singapore housing, living, staying & working in Singapore. Apartment, condo, house

 

 
  Principal Investigators   IMCB JUNIOR Investigators   IMCB Independent Fellow   research fellows   research assistants   OTHER Opportunities    
     
 

Postdoctoral Research Fellow Position

Date available: Immediate

Date posted: 8 April, 2014

A postdoctoral research fellow position is immediately available at the Zebrafish Translational Unit in IMCB. The successful applicant will be involved in an A*STAR JCO funded project and is required to work closely with fellow team members from IMRE. 
The ideal candidate should hold a Ph.D. in molecular biology, developmental biology, biochemistry or other relevant fields. Experience in working with zebrafish, developing disease models and bioimaging is desired. The successful candidate must be stimulated by interdisciplinary discussions and be motivated to develop and carry out strategies that assess outcomes of specific mission oriented research.

Examples of published research conducted by the Zebrafish Translational Unit in IMCB highlighting the varied approaches used to validate performance of novel fabricated nanomaterials are listed in references below.

References:

  1. You WH, Teh C, Tan H, Wong S-Y, Zhang Y, Korzh V, Li X, Wang J: PEO surface-decorated silica nanocapsules and their application in in vivo imaging of zebrafish RSC Adv 2012(2):12392-12399.
  2. Yan H, Teh C, Sreejith S, Zhu L, Kwok A, Fang W, Ma X, Nguyen KT, Korzh V, Zhao Y: Functional mesoporous silica nanoparticles for photothermal-controlled drug delivery in vivo. Angew Chem Int Ed Engl 2012, 51(33):8373-8377.
  3. Ma X, Teh C, Zhang Q, Borah P, Choong C, Korzh V, Zhao Y: Redox-Responsive Mesoporous Silica Nanoparticles: A Physiologically Sensitive Codelivery Vehicle for siRNA and Doxorubicin. Antioxid Redox Signal 2013.

Requirements:

  • Ph.D. from a well-recognized institution in Life Sciences/Biomedical Sciences.
  • Strong publication record in peer-reviewed journals.
  • The ability to work in a team and conduct independent research with excellent analytical, technical and problem solving skills.
  • Ability to present research progress at internal and external seminars/conferences.

Interested candidates are to email a detailed CV that includes research motivations, publication list and email address of at least 3 referees to Cathleen Teh (cathleen@imcb.a-star.edu.sg).

We regret that only shortlisted applicants will be notified.


Postdoctoral research fellow position

Date available: Immediate

Date posted: 24 February, 2014

A Postdoctoral research fellow position is available immediately at the IMCB Epigenetics and Cell fates Laboratory. The laboratory is interested in developing novel tools and strategies in deriving differentiated cell types via defined factors reprogramming.

Applicants with relevant background in Stem cell biology, Haematology, Neurobiolgy or related fields are invited to apply. Experience with Human ESCs differentiation and mouse work would be highly desirable. Successful candidates must be highly motivated, have passion for research and be able to work in an interdisciplinary environment.

Requirements:

  • Ph.D. from a well-recognized institution in Stem cell biology/Life Sciences/Biomedical Sciences
  • Strong publication record in peer-reviewed journals
  • Committed and able to work flexible hours
  • Ability to conduct high-quality independent research with excellent analytical, technical and problem solving skills.
  • Excellent communication, technical writing and presentation skills

Interested candidates are asked to send a cover letter detailing research motivations, CV, and the names and email addresses of three references to Jonathan Loh (yhloh@imcb.a-star.edu.sg). Applicants can visit the lab website to find out more (http://www.imcb.a-star.edu.sg/php/jl.php).

We regret that only shortlisted applicants will be notified.

References:

  1. Gore A et al. Somatic coding mutations in human induced pluripotent stem cells. (2011)
    Nature 471, 63-67.
  2. Agarwal S et al. Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients. (2010) Nature 464, 292-296.
  3. Loh YH et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. (2006) Nature Genetics 38, 431–440.





Research Fellow
or Lab Biologist

Date available: Immediate

Date posted: 9 January, 2014

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences funded by the Agency for Science, Technology and Research (A*STAR). Its mission is to develop and foster a vibrant research culture for cutting-edge basic biomedical sciences. IMCB’s research activities focus on the areas of Animal Models of Development and Disease, Cancer Genetics and Therapeutics, Cell Biology in Health and Disease, and Structural Biology and Drug Discovery. IMCB is continuously looking out for talented people to contribute to its success. We are now inviting suitable candidates to apply for the following position.

Bacterial filament systems play vital roles in prokaryotic cell division and DNA segregation and are closely related to their eukaryotic counterparts, actin and microtubules. The group studies the structure and function of bacterial filament systems addressing questions ranging from evolutionary design, nano-machines to intelligent drug design. IMCB offers first class facilities, including protein expression and purification, light/electron microscopy and X-ray crystallography. We are a vibrant group of biologists interested in uncovering how bacterial cells work at a molecular level. We are now inviting suitable candidates to apply for the following position:

Lab Biologist or Research Fellow
(Job Ref : BMSI/IMCB/BR/LB-RF/09012014)

Duties and responsibilities:

Lab Biologist - this position requires application of routine molecular biology techniques such as protein expression and purification.

Research Fellow - this position would provide the opportunity to work on novel filament systems, which are ready to be characterized by various biochemical and biophysical methods, with a high possibility to obtain publications.

Both positions are on a one-year contract with possible renewal.

Minimal Requirements:

  • Lab Biologist - Diploma in Biological Sciences; Research Fellow – PhD holder
  • Preferably with experience as laboratory technician in the biological/biomedical field
  • Good technical and communication skills
  • Ability to work with timelines
  • Ability to work independently and as part of a team

Interested applicants are welcome to fax or write in with a detailed resume, supporting documents and contact numbers by to: Human Resources Department, Institute of Molecular and Cell Biology, 61 Biopolis Drive, Level 2, #02-02, Proteos Building, Singapore 138673; Fax: 6779 1117 or email to : recruit@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.




Postdoctoral Research Fellow position

Date available: immediately

Date posted: : 18 November 2013

One Research Fellow (Post Doctoral) position is available in the Humanized Mouse Unit (HMU) of the Institute of Molecular and Cell Biology (IMCB), A*STAR, Singapore.

The Humanized Mouse Unit (HMU) studies human infectious diseases and cancers using a combination of biochemical, molecular and immunological approaches in human-mouse chimera models. Our research is a fast-developing area in biomedical and bioengineering science, which is critical to understand and develop therapeutics to many human specific diseases. For an overview of our research, please visit our HMU, IMCB intranet for more information (Website: http://www.imcb.a-star.edu.sg/php/ittd-hmu.php).

Responsibilities

  • Undertake independent research under the direction of the Group Leader (GL) and with other lab members.
  • Assist the GL in quality control for experiments, data analysis, manuscript preparation, grant applications and lab management.
  • Assist the GL in guiding and training students and junior research staff.
  • Present research achievements at internal and external seminars and conferences.

Qualification / Requirements

  • The candidate should be self-driven to pursue a scientific career, motivated, independent and be passionate about immunology research.
  • Hold a doctoral degree or be in the final stage of completing doctoral study in a relevant field of immunology or virology.
  • Good knowledge and concept of immunology and possess demonstrated research experience and achievement.
  • Good English proficiency and technical writing skills.
  • Prior experience in working with mice, flow cytometry, immunofluorescence etc.

Applicants may email a detailed CV containing your list of publications, as well as reference letters from at least 2 referees to :
Dr. Qingfeng Chen, qchen@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.

 



Postdoctoral Research Fellow position

Date available: immediately

Date posted: : 2 October  2013

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences funded by the Agency for Science, Technology and Research (A*STAR). Its mission is to develop and foster a vibrant research culture for cutting-edge basic biomedical sciences. IMCB and Nanyang Technological University (NTU) have together set up the Joint Center for Biomedical Structural Biology, which is fully equipped for protein purification, biophysics and protein crystallization work. The center is located at Proteos building within IMCB.

Prof Pär Nordlund from the Joint Center of Biomedical Structural Biology is now recruiting talented Postdoctoral Research Fellows. The group uses a Systems Structural Biology approach to study function and mechanism of proteins in signaling, metabolism and membrane transport pathways with implications for cancer and inflammation. The group also consists of a structure based drug design team. The laboratory is well equipped with state-of-the-art instruments for protein chemistry and biophysics, crystallography and cell biology, and is supported by a protein production platform.

Currently, two Postdoctoral positions are available (located at IMCB, Biopolis).

  1. Structure based drug design: The applicant will join a team exploring novel avenues for fragment based ligand design. The applicant should have a strong background in biophysics and protein science techniques and concepts. Knowledge of X-ray crystallography is ideal but not a requirement.

  2. Biophysical ligand screening in cells: The applicant will join a team exploring a new breakthrough technology for monitoring drug actions in cells and tissues. The applicant should be a strong cell biologist with extensive experiences working with drugs and chemical probes.

Interested candidates are invited to send a full CV, including a publication list, together with contact information of three references before 15th November 2013 to: Prof. Pär Nordlund (PNORDLUND@ntu.edu.sg) or Dr. Andreas Larsson (andreas.larsson@ntu.edu.sg).

Only shortlisted candidates will be contacted.

Selected recent publications:

Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay. Martinez Molina D, Jafari R, Ignatushchenko M, Seki T, Larsson EA, Dan C, Sreekumar L, Cao Y, Nordlund P.
Science.
2013 Jul 5;341(6141):84-7.

Fragment-based ligand design of novel potent inhibitors of tankyrases. L
arsson EA, Jansson A, Ng FM, Then SW, Panicker R, Liu B, Sangthongpitag K, Pendharkar V, Tai SJ, Hill J, Dan C, Ho SY, Cheong WW, Poulsen A, Blanchard S, Lin GR, Alam J, Keller TH, Nordlund
P. J Med Chem.
2013 Jun 13;56(11):4497-508



Research Fellow Position in Structural Biology

Date available: immediately

Date posted: 27 June 2013

We are seeking an enthusiastic and self-motivated postdoctoral research fellow to work on structural and functional analysis of proteins involved in RNA metabolism and the Hippo signalling pathway. Candidates with an interest in the development of small molecules to target the Hippo pathway for cancer therapeutics are also welcome. Candidates must have experience in protein or nucleic acid structure determination by X-ray crystallography and demonstrated success in molecular biology and protein expression using insect or mammalian cells.  Excellent communication skills are essential. Our group is part of the Joint Structural Biology Centre between Institute of Molecular and Cell Biology (IMCB) and Nanyang Technological University with excellent shared facilities and dedicated access to beamlines at ESRF in France and SLS in Switzerland. Further information is available at: http://www.imcb.a-star.edu.sg/php/shw.php.  Applicants must have a PhD with a strong publication record. Please send CV, including the names and addresses of three references, to: Dr. Haiwei Song haiwei@imcb.a-star.edu.sg .

Only shortlisted candidates will be contacted.