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  Principal Investigators   IMCB JUNIOR Investigators   RESEARCH FELLOWS   research/Lab Officers   OTHER Opportunities    
     
 


CETSA NTU Research Officers

Date available: immediate

Date posted: 5 Jan 2016

We are looking for talented Project officers (2 positions)

Workplace:  School of Biological Sciences, NTU @ One North
Form of employment: Full time, Project employment
Start date: ASAP

General description:

Our group is interested in application of thermally induced unfolding of proteins in drug target deconvolution. Thermal stability assays explore the observation that a purified protein in a specific state has a distinct unfolding behaviour and ligand engagement changes protein heat stability triggering melting shift.  We setup in School of Biological Sciences, NTU @ One North together with IMCB/A*STAR new mass spectrometry based cellular thermal shift assay (MS-CETSA) platform for drug discovery. With this approach biochemical changes due to e.g. drug treatment can be globally monitored to discover protein targets/off targets and novel biomarkers proteome wide. Such MS-CETSA experiments allow parallel biochemical profiling of a large number of proteins in cell lysates/whole cells as well as individual patient sample. The work is distributed into two teams; one working with cell biology, molecular biology techniques and the other focusing on quantitative mass spectrometry based proteomics.

Job description:

The cell biology team will be responsible for preparing experiments involving cell culture, Thermal Shift Assays for Mass spectrometry based drug/new compound screening.

Qualifications:

  • You have minimum a B.Sc within the field of biochemistry, molecular biology, biotechnology or equivalent.
  • Hands on experience from laboratory work in the field of molecular biology, cell biology or protein chemistry is a requirement.
  • Mass spectrometry experience is important but not crucial
  • You are able to work in a structured mode and can adhere to stringent timelines.
  • High-throughput work requires strict documentation and we expect you to have a thorough appreciation of the merits of GLP.

Please send your resume and CV to the email address: CETSA_MS@ntu.edu.sg

Par Nordlund (NTU) / Radoslaw Sobota(IMCB)

We regret that only shortlisted applicants will be notified.




Laboratory Officer

Date available: immediate

Date posted: 24 Nov 2015

The Advanced Molecular Pathology Laboratory provides key support in conducting cutting-edge biomedical research and development with specific focus on rodent histology. As part of the dynamic team, you will be responsible for providing services in this laboratory to support the needs of researchers.

Responsibilities:

  • Operate specialised laboratory equipment to provide service to the research community.
  • Provide high quality technical services to researchers in the areas of complex tissue collection and processing procedures, as well as other laboratory procedures such as necropsy, embedding, cryotomy, microtomy, staining, etc.
  • Maintain equipment, consumables, etc in good working order to ensure an uninterrupted service whenever possible.
  • Involve in QA audit for GLP compliance.
  • Handle routine laboratory administration.

Requirements:

  • Diploma in Life Sciences, Biological Sciences or a related field.
  • Good basic laboratory skills and manual dexterity.
  • Familiarity with histopathology techniques and GLP would be an advantage.
  • Meticulous and organised with an ability to multi-task.
  • Good communication, interpersonal and analytical skills.
  • Able to work independently and as a team in a fast-paced environment.
  • Willing to work in a service based environment and provide technical service support.

IInterested candidates are to email a detailed CV that includes two referees to recruit@imcb.a-star.edu.sg.


We regret that only shortlisted applicants will be notified.





Research Officer

Date available: immediate

Date posted: 17 Nov 2015

A Research Officer position is available at A*STAR IMCB’s Laboratory for Multiscale Molecular Diagnostics. Integrating advances in molecular biology, materials science, and biomedical engineering, the laboratory seeks to develop novel micro- and nanotechnologies to empower biomarker discovery and its clinical translation. Please visit our lab website to find out more (http://www.imcb.a-star.edu.sg/php/iif-hs.php)

Job Responsibility:
Applicants with relevant background in Bioengineering, Chemical Engineering, Chemistry, Electrical Engineering or related fields are invited to apply. Successful candidates must be interested in translational research, highly motivated, and be able to work in an interdisciplinary environment.

Requirements:

  • Bachelor’s degree from a well-recognized institution.
  • Experience in microfabrication, nanotechnology and microfluidics will be desirable
  • Excellent analytical, technical and problem solving skills.
  • Excellent organizational skills.
  • Committed and motivated.

Interested candidates should send a cover letter detailing your research motivations, CV, and the names and contact information of three references to Dr. Huilin SHAO (hshao@imcb.a-star.edu.sg).

We regret that only shortlisted candidates will be notified.





Research Officer

Date available: immediate

Date posted: 11 Nov 2015

The Institute of Molecular and Cell Biology (IMCB) is a research institute within the Agency for Science, Technology and Research (A*STAR). Its mission is to foster a vibrant research culture for cutting-edge biomedical sciences. IMCB’s research activities focus on four major fields: Animal Models of Development and Disease, Cancer Genetics and Therapeutics, Cell Biology in Health and Disease, and Structural Biology and Drug Discovery.

Responsibilities
Applications are invited for a Research Officer position at the lab for microRNA Models of Cancer and Neurodegenerative Disease.

The work will involve high-resolution video imaging and analysis of behaving flies, climbing/movement assays and brain dissections and immunohistochemical analysis, as part of a multidisciplinary collaborative project between biologists, machine vision computer scientists and engineers. The candidate may also be required to help out with other related projects as necessary. Other important responsibilities include upkeeping of lab reagents/equipment and fly stocks, and other lab housekeeping and administration tasks.

Candidates should be highly motivated, conscientious and able to work independently, with good organisational, verbal and interpersonal skills. Biologists with an interest and experience in tinkering with cameras and computers are the ideal candidate. If keen to develop your scientific career, you are highly encouraged to participate in scientific discussions and data analysis.

This is an excellent opportunity for graduates interested in pursuing further studies in biomedical research to work on an independent research project, with guidance from a multi-disciplinary group of scientists.

  Qualification & Expertise:

  • A good Honours degree in Life Sciences, Biology, Neuroscience, Bioengineering or other biomedical science-related fields.
  • Committed and motivated
  • Interest in an interdisciplinary approach to biology and biomedical science
  • Excellent skills in imaging and tissue dissection
  • Some familiarity with cameras and computer languages
  • Experience with designing, planning and carrying out experiments
  • Able to work and communicate effectively with others
  • Able to plan tasks independently

IMCB provides a competitive remuneration package commensurate with your specific qualifications and experience.  We welcome interested applicants to submit a brief cover letter, full CV and contact details of two professional referees to Dr Sherry Aw (syaw@imcb.a-star.edu.sg).

Applications will be accepted until the position is filled. We regret that only shortlisted applicants will be notified.





Research Officer
(Asia Biotech IMCB Molecular Biology Lab, AIMBL)

Date available: immediate

Date posted: 27, October 2015

The Position:

  • You will set up a new lab and maintain its routine work.
  • Support and coordinate basic research and admin activities
  • The candidate must be a proactive player in decisions.
  • Be able to establish operational support for Supervisor and other fellow lab members
  • Cell Culture knowledge is essential in this role.

Qualification & Expertise:

  • Bachelor or M.Sc of Biochemistry, Biotechnology, Biomedical or Life Science related is required
  • Min. 3 years experience in Life Science or related industry
  • Excellent people management skills
  • Excellent oral/written communication skills is an asset.
  • Good presentation skills

Interested candidates are invited to send a brief cover letter, curriculum vitae to
recruit@imcb.a-star.edu.sg
  

We appreciate your understanding that only shortlisted applicants will be notified.




Research Officer Position

Date available: immediate

Date posted: 16, October 2015

A Research Officer position is available at A*STAR IMCB’s Laboratory for Multiscale Molecular Diagnostics. Integrating advances in molecular biology, materials science, and biomedical engineering, the laboratory seeks to develop novel micro- and nanotechnologies to empower biomarker discovery and its clinical translation. Please visit our lab website to find out more (http://www.imcb.a-star.edu.sg/php/iif-hs.php))

Job Responsibility:
Applicants with relevant background in Life Sciences, Biology, Bioengineering or related fields are invited to apply. Successful candidates must be interested in translational research, highly motivated, and be able to work in an interdisciplinary environment.

Requirements:

  • Diploma or Bachelor's degree from a well-recognized institution.
  • Cell and molecular biology background.
  • Experience in cell culture, Western blotting, ELISA, DNA/RNA workflow, primer design, qPCR will be desirable.
  • Excellent analytical, technical and problem solving skills.
  • Excellent organizational skills.
  • Committed and motivated.

Interested candidates should send a cover letter detailing research motivations, CV, and the names and contact information of three referees to Dr. Huilin SHAO (hshao@imcb.a-star.edu.sg).

We regret that only shortlisted candidates will be notified.


Research Officer Position

Date available: immediate

Date posted: 13, October 2015

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences funded by the Agency for Science, Technology and Research (A*STAR). Its mission is to develop and foster a vibrant research culture for cutting-edge basic biomedical sciences. IMCB's research activities focus on the areas of Animal Models of Development and Disease, Cancer Genetics and Therapeutics, Cell Biology in Health and Disease, and Structural Biology and Drug Discovery. IMCB is continuously looking out for talented people to contribute to its success.

A research officer position is immediately available at the Monoclonal Antibody Unit in IMCB. The successful applicant will be primarily involved in a project studying hepatitis viral infection of mice but is required to assist in other projects whenever necessary. A 1-year contract will be offered in the first instance.

The successful candidate must be stimulated by interdisciplinary discussions and be motivated to develop and carry out strategies that assess outcomes of specific mission oriented research.

Requirements:

    • At least a Bachelor's degree (preferably with honours) in Biological Sciences or related fields
    • Must be able to communicate well in English.
    • Research experience in virology and/or cell biology is preferred.
    • Prior experience in mouse experimentation is preferred.
    • Willing to work with live virus and mouse models.
    • Able to assist in laboratory administrative and management tasks including procurement and safety issues.
    • Able to work in a team and conduct independent research with excellent analytical, technical and problem solving skills.

    Read more about our work at: http://www.imcb.a-star.edu.sg/php/ittd-mau.php

    Interested candidates are to email a detailed CV that includes two referees to recruit@imcb.a-star.edu.sg. We regret that only shortlisted applicants will be notified.


Research Officer Position

Date available: 1, November 2015

Date posted: 29, September 2015

A Research Officer position is available at the A*STAR IMCB – Laboratory of Chromatin Dynamics & Disease Epigenetics. The laboratory is interested to study how chromatin deficiencies underlie human diseases such as cancer and developmental disorders. A comprehensive understanding of epigenetic-based mechanisms will allow us to: (1) elucidate disease mechanisms that will guide the development of new epigenetic-based therapeutic modalities, and (2) utilize this knowledge to re-engineer cellular phenotypes through manipulation of chromatin structure and function, for regenerative medicine applications. We employ mouse and stem cell models for our studies.

We are looking for a motivated Research Officer with a keen interest in developmental biology and/or biochemistry. He/She will perform general lab managerial duties and assist the PI and postdocs to conduct biochemical and molecular biology experiments. He/She will also have opportunities to pursue independent research projects.

Specific requirements:

(1) Possess a Bachelor’s degree in Life/Biomedical Sciences from a recognized University.
(2)  Familiarity with routine lab techniques such as mammalian cell culture and molecular biology       (Western blotting, Q-PCR, cloning, protein expression, etc).
(3)  Candidates with prior experience in human stem cell cultures, mouse genetics, or protein       biochemistry are highly desirable.
(4)  Independent with good organizational skills, and an effective team player.

Salary and benefits will be commensurable to educational qualifications, track record and working experience. Interested applicants should email his/her curriculum vitae, a cover letter addressing research interest, experience and skills, and contact information of three referees to
Dr. Wee-Wei Tee
(wwtee@imcb.a-star.edu.sg)
or Human Resources Department (recruit@imcb.a-star.edu.sg).

We regret that only shortlisted candidates will be notified.



Laboratory/Research Officer

Date available: 1 October 2015

Date posted: 7, September 2015

The Neurotherapeutics laboratory is looking for a motivated Laboratory/Research Officer.

Qualifications: Diploma or degree in Life Science or Biomedical Science.

Job description: The successful candidate will be a dynamic and service-minded person, preferably with experience working in a research lab. He/She will have a strong presence in the laboratory by assisting with general lab duties, including mammalian cell culture and molecular biology experiments, as well as conducting research together with other lab members.

Applications including CVs should be sent by email to Dr. Shi-Yan Ng (syng@imcb.a-star.edu.sg) or HR (recruit@imcb.a-star.edu.sg).

We regret that only shortlisted applicants will be notified.



Research Officer

Date available: Immediate

Date posted: 7, September 2015

The Disease Modelling and Therapeutics lab is looking for a motivated Research Officer with expertise in tissue culture and molecular biology work. This position involves:

  • Cell culture of human ES/iPS cells
  • Various molecular assays including, but not limited to, PCR, Real time PCR and Western blot
  • Providing general support in laboratory supplies, procurement and inventory management

Requirements:

  • A Bachelor's degree in Life Sciences or Biological Sciences
  • Possess molecular biology background and should be capable of performing routine experiments (DNA/RNA extraction & expression, qPCR, immunohistochemistry, Western blotting, etc)
  • Good computer and laboratory data analysis and recording skills are necessary
  • Outstanding laboratory and project management skills are desired
  • Enthusiastic, committed and possess good working attitude
  • Prior experience in embryonic stem cell culture would be an advantage
  • Applicants should be able to multitask and work independently
  • Applicants should be passionate about science and is able to work on weekends

Interested candidates are welcome to email a brief cover letter, CV, and the names and email addresses of 3 referees to Boon Seng SOH (bssoh@imcb.a-star.edu.sg) or Human Resource Department (recruit@imcb.a-star.edu.sg)

We regret that only shortlisted applicants will be notified.



Laboratory Officer / Research Officer

Date available: Immediate

Date posted: 11, August 2015

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences primarily funded by the Agency for Science, Technology and Research (A*STAR). Its mission is to develop and foster a vibrant research culture for cutting-edge basic biomedical sciences.
The laboratory of Neurotechnology is looking for a motivated research assistant to help with work in non-human primate research.

Your responsibilities will include:

  • Aid researchers in surgeries of rats and monkeys
  • Ability to work with all members of the veterinary and research team
  • Good interpersonal skills

Requirements:

  • Diploma or Degree in any science related field
  • Ability to work with all members of the veterinary and research team
  • Good interpersonal skills

We welcome interested applicants to submit a full CV and cover letter with names/contact details of two referees to: camilo@nus.edu.sg

We regret that only shortlisted applicants will be notified.



Research Officer position in IMCB, A*STAR

Date available: Immediate

Date posted: 1, July 2015

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences primarily funded by the Agency for Science, Technology and Research (A*STAR). Its mission is to develop and foster a vibrant research culture for cutting-edge basic biomedical sciences. IMCB's research activities focus on four major fields: Animal Models of Development and Disease, Cancer Genetics and Therapeutics, Cell Biology in Health and Disease, and Structural Biology and Drug Discovery. IMCB is continuously looking out for talented people to contribute to its success.

The laboratory of Drug Development Unit (DDU) is looking for a motivated Research Officer who has either bioanalysis or molecular biology background/training to support the effort in research and development of novel therapeutic agents.

Requirements:

  • A degree in biological sciences or chemistry or a related discipline
  • Experience in a Biology or Chemistry lab or with relevant industrial attachment is preferred
  • Experience in handling small animals (e.g., mouse/rat) is an advantage
  • Awareness of workplace health and safety
  • Good organizational skills and good work attitude
  • An ability to multi-task and work independently
  • Applicant should be capable of collecting, handling and/or analyzing biological samples (e.g., cancer cells/tumor tissues, mouse/rat tissues, zebrafish, etc.) after on-the-job training
  • Applicant with molecular biology background should be capable of performing routine experiments (cell culture, cellular assays, western blotting, etc.)
  • Applicant with bioanalysis background should be capable of using LC-MS/MS for small molecule ADME/PK analysis.

Interested candidates are welcome to email a brief cover letter, CV, and the name and email address of referees to Haishan WANG (hswang@imcb.a-star.edu.sg) or Human Resources Department (recruit@imcb.a-star.edu.sg)

We regret that only shortlisted applicants will be notified.



Research Officer

Date available: Immediate

Date posted: 22, June 2015

The FB lab is looking for a motivated Research Officer who will support two postdocs in their projects and running of the RNAi facility. The successful candidate will help in performing cell biology and biochemistry experiments, liaising with collaborators, coordinating the usage and management of facility equipment including learning to use our high-throughput microscopes, and maintaining some paperwork for bookkeeping purposes.

Reference: http://www.imcb.a-star.edu.sg/php/ittd-t-rnai.php

Requirements:

  • Degree in Biological Sciences or equivalent
  • Good organizational skills, ability to work independently and a good work attitude
  • Is enthusiastic, committed, and a quick learner
  • Has good written and spoken communication skills
  • Is generally proficient with computers

Interested candidates are invited to send a brief cover letter detailing research motivation, curriculum vitae, and the names and email addresses of three referees to:

Human Resources Department, Institute of Molecular and Cell Biology, 61 Biopolis Drive, Level 2, #02-03, Proteos, Singapore 138673; Fax: 6779 1117 or email: recruit@imcb.a-star.edu.sg

We appreciate your understanding that only shortlisted applicants will be notified..