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  Principal Investigators   IMCB JUNIOR Investigators   RESEARCH FELLOWS   research/Lab Officers   OTHER Opportunities    
     
 


Research Officer
– PN Lab

Date available: immediate

Date posted: 20 July 2016

A research officer position is available immediately in the joint IMCB/NTU laboratory headed by Prof. Pär NORDLUND, and is located in IMCB at One North. The laboratory focuses in medical structural biology and drug development, and compromises of a drug discovery team and a bioengineering team supported by a HTP protein production platform. It is equipped with state-of-the-art instruments for protein chemistry and biophysics, crystallography and cell biology. Selected applicant will work in a newly established multidisciplinary team comprising of structural biologist, cell & molecular biologists, mass spectrometry technologists and bioinformaticians. He or she will be involved in projects spearheaded by Dr. Chris Soon Heng TAN where state-of-the-art technologies will be applied to identify unknown drug targets and to discover protein machines that modulate disease progression and drug response.

Job Responsibilities::

  • Perform molecular biology and biochemistry experiments such as cell culture, cloning, western blot, immunofluorescence, protein expression and purification.
  • Perform sample preparation for mass spectrometry analysis and basic MS data processing.
  • Assist in laboratory administrative and management tasks including procurement.

Job Requirement:

  • Diploma in Biomedical Science or Biotechnology or Pharmacy/Pharmaceutical Science or related disciplines.
  • At least two years of experience working in a molecular biology or biochemistry laboratory.
  • Keen interest to pick up new technical skills and acquire new knowledge.

Interested candidates should send a full CV together with contact information for two references to: Dr. Chris Soon Heng TAN (cshtan@imcb.a-star.edu.sg)



Research Officer – BL Lab

Date available: immediate

Date posted: 20 July 2016

The Human Embryology and Genetics laboratory, headed by Dr. Bruno Reversade, investigates human embryonic development and its associated genetic diseases. By addressing rare human pedigrees the group examines inherited disorders that produce birth defects. The successful candidate will be involved in laboratory work focusing on rare Genetic Orphan Disease (GOD).

Job Responsibilities::

  • Providing technical support to the researchers of the human embryology and genetics laboratory
  • Performing experiments involving molecular biology, cell and animal based techniques.
  • Ensuring good maintenance of laboratory equipments and participating in procurement activities

Job Requirements:

  • Bachelor degree or diploma in Biomedical Science with work experience
  • Candidates with working experience in a laboratory environment is preferred
  • Able to work well in a team
  • Organized, dedicated and reliable

Please send curriculum vitae (CV) and full contact information of at least two referees, mentioning “Research Officer” in the subject of the application to Dr Xue Shifeng: sfxue@imcb.a-star.edu.sg


We regret that only shortlisted candidates will be notified.




Central Imaging Facility Microscopy
(Research Officer / Scientist)

Date available: immediate

Date posted: 20 July 2016

The IMCB Central Imaging Facility (CIF) is an Infrastructure, Technology and Translational Division (ITTD) unit that supports the imaging and image analysis needs of IMCB.

The CIF is seeking suitably qualified candidates to apply for the position of
Central Imaging Facility Microscopy Research Officer or Scientist

Job description:

  1. Point of contact for advice and help on microscopes.
  2. Train, advise and support users in the application of various microscopy techniques to biomedical research: from basic microscopy (brightfield, contrast enhancing techniques, widefield fluorescence and confocal) to advanced microscopy (F-techniques, 3D imaging, live-cell imaging, super‐resolution microscopy) and quantitative image analysis.
  3. Troubleshoot, provide basic maintenance and upkeep of microscope systems.
  4. Manage booking system.
  5. Liaise with the manufacturers/vendors for repairs, upgrades, application support and new developments.
  6. Hold the N3 laser license for IMCB.
  7. Propose a budget for maintenance, repairs, replacement of existing equipment and new acquisitions, and manage the approved budget.
  8. Develop collaborative research projects with research staff on specific scientific projects.
  9. Work with CIF Imaging Informatics Research Scientist to advise IMCB researchers on image acquisition, data handling, image processing and analysis and data presentation.
  10. Monitor safe working conditions and implement measures as required.
  11. Join the Safety Committee.
  12. Perform other administrative duties.

Requirements:

  1. Possess at least a B.Sc. (for Research Officer) or Ph.D (for Research Scientist) in one of the Life Sciences.
  2. Have at least 3 years hands-on experience in confocal and light microscopy.
  3. Good understanding of the principles of microscopy.
  4. Possess excellent communication and organizational skills.
  5. Committed to exceeding quality standards and providing exceptional services.

nterested applicants are to apply through:

https://astar.aqayo.com/site-YXN0YXJ8MjA/member_offerdetail.jsp? siteid=YXN0YXJ8MjA&requisitionuid=fbfbf22f20fbaa405d51ca7ea44a815b19801eca

or

https://astar.aqayo.com/site-YXN0YXJ8MjA/member_offerdetail.jsp? siteid=YXN0YXJ8MjA&requisitionuid=f619ac26a1c53601a62e40a9f06c7ca89ce8f9e9



Research Officer - PRK lab

Date available: immediate

Date posted: 14 July 2016

Job Summary:
A research officer position is immediately available in the Cell Division and Cancer Laboratory at IMCB. The successful applicant will be involved in projects studying the regulation of the cell cycle in vivo by combining mouse genetics with cell biology and biochemistry. He/she is also required to assist in other projects whenever necessary and manage administrative duties of the laboratory.

Job Responsibilities:
(Day to day job)
Responsibilities include:

  • Laboratory maintenance including laboratory organization and cleanliness, up keeping of laboratory consumables/reagents/equipment, placing purchase orders, etc.
  • Laboratory administration including purchase payments, proper record keeping of the consumables purchased, safety report writing, etc.
  • Perform or assist in experiments.
  • Maintenance of mouse colony.

Job Requirements:

  • (Education)
    -   At least a Bachelor’s degree in Biological Sciences or science-related fields.
  • (Skill set)
    -   Well organized, talented in bench work, versed in administration, willing to work hard.
  • (Working experience)
    -   Candidates with prior laboratory experience are preferred.
  • Desirable attributes)
    -   Willing to work with mouse models.
    -   Able to work and communicate effectively with others.
    -   Able to plan tasks independently.



Please send CV, including the names and addresses of three references to: Dr. Philipp Kaldis kaldis@imcb.a-star.edu.sg





Research Officer - TBP

Date available: immediate

Date posted: 22 Jun 2016

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences funded by the Agency for Science, Technology and Research (A*STAR). Its mission is to develop and foster a vibrant research culture for cutting-edge basic biomedical sciences.

Research Officer
A research officer position is immediately available at the Translational Biomedical Proteomics Laboratory in IMCB. The successful applicant will be primarily involved in mass spectrometry (MS) sample preparation and MS data processing.

Candidates should possess a Bachelor of Science in biochemical/life science/chemistry related areas and be keen in learning mass spectrometry-based proteomics technology and basic computational proteomics (training will be provided). Good organizational skills, work attitude, team work and communication skills are essential.

Interested candidates should contact jayanthag@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.

 




Research Officer (Bioinformatician)

Date available: immediate

Date posted: 31 May 2016

Job Summary:
The individual in this position will conduct bioinformatics and statistical analysis of next generation sequencing data and assist data interpretation and visualization in collaboration with molecular biologists.

Job Responsibilities:
(i)   Epigenetic data analysis using chromatin immunoprecipitation coupled with NGS (ChIP-seq)
(ii)  Transcriptomic data analysis such as differential gene expression and splice variant detection       (RNA-seq)
(iii) DNA variant calling.

Job Requirements:

  • (Education) Master’s degree, or bachelor’s degree with >5 years of experience

  • (Skill set)
    Familiarity scripting in perl / python / C++ / Java, statistical programming in R is a must. Experience in SQL to query and manage large databases is a plus.

  • (Working experience)
    Preferably 2 years.

  • (Desirable attributes)
    Strong team player. Interest in molecular biology. Excellent organization and communication skills.

Interested candidates are asked to send a cover letter detailing your research motivations, CV, and the names and email addresses of three references to Hyungwon (hwchoi@imcb.a-star.edu.sg)




Research Officer (Bioinformatics)

Date available: immediate

Date posted: 12 Apr 2016

Job Summary:
Our laboratory uses a comparative genomics approach to understand the structure, function and evolution of human and other vertebrate genomes. Our projects involve sequencing and assembling whole genomes and transcriptomes using NGS platforms, genome annotation, gene and protein family evolution; prediction and assay of conserved noncoding elements; differential gene expression, sequencing human whole exome and whole genome using NGS; and prediction and validation of variants associated with diseases. The successful candidate will be involved in various comparative genomics projects, and will be working as part of a team of bioinformaticians and biologists. 

Job Responsibilities:
Processing and assembling genome and transcriptome reads generated on next-generation sequencers, genome annotation, gene expression analyses based on RNA-seq, whole genome alignments, prediction of conserved noncoding elements, creation and maintenance of relational databases.

Job Requirements:

  • Master's degree in bioinformatics or computational biology
  • Experience in processing and assembling 'next-generation' sequences.
  • Familiar with genome annotation using Ensembl and Maker pipelines
  • Analysing differential expression of genes based on RNA-seq data
  • Perform variant prediction and validation
  • Experience in Perl / Java / C++ /Python programming, ideally to the level of object-oriented and database programming, use of modules, etc
  • Strong programming skills in UNIX and MySQL
  • Strong knowledge of a wide range of bioinformatics tools (e.g. Trinity, CABOG, Cufflinks, EMBOSS, Phylip, HMMER) and databases (e.g. Ensembl, Refseq, UniGene, UniProt, PDB, Pfam)
  • Motivated to explore and learn new bioinformatics tools
  • Possess excellent communication skills
  • A strong team player

Interested candidates are to apply through:
https://astar.aqayo.com/apply/48878e7-20/Research_Officer_Bioinformatics




Research Officer

Date available: immediate

Date posted: 6 Apr 2016

  • Major responsibilities as a Research Officer in SIPRAD will include hands-on execution of in vivo experiments to evaluate compounds for efficacy and toxicity in translatable animal models of retinal angiogenetic diseases with clinically-relevant endpoints, especially with experience to handle rabbit.
  • Provide broad level administrative and operational support to Principal Investigator, include placing orders, fixed assets management, liaising with vendors.

Job Requirements:

  • Minimum Bachelor of Science in Biomedical related fields.
  • 2-3 years of experience in preclinical research in ophthalmology or imaging related field of specific academic/industrial experience.
  • Working knowledge in ocular pharmacology, background in ophthalmology preferred.
  • Comfortable in handling live animals (rabbits)
  • Hands-on experience in animal handling, surgical procedures, in vivo efficacy assessments, IV and IP dosing, blood and tissue sampling techniques.
  • Experienced in conduct data interpretation and reporting of study results and conclusions.
  • Demonstrated ability to solve scientific problems creatively, effectively and independently.
  • Good written and oral communication skills.
  • Good organizational skills and work attitude.

Interested candidates are to apply through: https://astar.aqayo.com/apply/c839f0b-20/Research_Officer_SIPRAD_IMCB

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice.

We regret that only shortlisted applicants will be notified.


Research Officer

Date available: immediate

Date posted: 6 Apr 2016

Major responsibilities as a Research Officer in SIPRAD will include hands-on execution of in vivo experiments to evaluate compounds for efficacy and toxicity in translatable animal models of retinal angiogenetic diseases with clinically-relevant endpoints, especially with experience to handle rabbit.

Job Requirements:

  • Minimum Bachelor Degree in Pharmacology, Veterinary Technologly or equivalent.
  • 2-3 years of experience in preclinical research in ophthalmology or imaging related field of specific academic/industrial experience.
  • Working knowledge in ocular pharmacology, background in ophthalmology preferred.
  • Experimental ocular imaging such as fundus camera, slit lamp and ocular coherence tomography (OCT).
  • Hands-on experience in animal handling, surgical procedures, in vivo efficacy assessments, IV and IP dosing, blood and tissue sampling techniques.
  • Experienced in conduct data interpretation and reporting of study results and conclusions.
  • Demonstrated ability to solve scientific problems creatively, effectively and independently.
  • Good written and oral communication skills.
  • Good organizational skills and work attitude.

Interested candidates are to apply through: https://astar.aqayo.com/apply/3f60257-20/Research_Officer_SIPRAD_IMCB

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice.

We regret that only shortlisted applicants will be notified.



Research Officer - MAU lab

Date available: immediate

Date posted: 3 Mar 2016

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences funded by the Agency for Science, Technology and Research (A*STAR). Its mission is to develop and foster a vibrant research culture for cutting-edge basic biomedical sciences. IMCB’s research activities focus on the areas of Animal Models of Development and Disease, Cancer Genetics and Therapeutics, Cell Biology in Health and Disease, and Structural Biology and Drug Discovery. IMCB is continuously looking out for talented people to contribute to its success.

Research Officer

A research officer position is immediately available at the Monoclonal Antibody Unit in IMCB. The successful applicant will be primarily involved in a project studying hepatitis viral infection of mice but is required to assist in other projects whenever necessary. A 1-year contract will be offered in the first instance.

The successful candidate must be stimulated by interdisciplinary discussions and be motivated to develop and carry out strategies that assess outcomes of specific mission oriented research.

Responsibilities::

  • Perform or assist in molecular biology and biochemistry experiments such as cell culture, cloning, protein expression and purification, Western blot and immunofluorescence analyses
  • Lab maintenance: roles include placing orders, fixed assets management,
  • Performing preventive maintenance and calling for repairs

Requirements:

Candidates should possess a Bachelor of Science in biomedical related areas
Candidate should be comfortable in handling live animals (mice)
Candidate should have good organizational skills and work attitude
Candidate should have good technical and communication skills

Read more about our work at: http://www.imcb.a-star.edu.sg/php/ittd-mau.php

Interested candidates are to apply through:
https://astar.aqayo.com/apply/8dcc9c9-20/Research_Officer_IMCB

We regret that only shortlisted applicants will be notified.





Research Officer - SC lab

Date available: immediate

Date posted: 18 Feb 2016

Applications are invited for a Research Officer position at the lab for microRNA Models of Cancer and Neurodegenerative Disease.

The candidate will be involved in projects related to neurodegeneration disease models in Drosophila. Other important responsibilities include upkeeping of lab reagents/equipment and fly stocks, and other lab housekeeping and administration tasks.

Candidates should be highly motivated, conscientious and able to work independently, with good organisational, verbal and interpersonal skills.

Requirements:

  • An undergraduate degree in Life Sciences, Biology, Neuroscience, or other biomedical science-related fields.
  • The candidate must be proficient in these lab techniques:
    -   Drosophila genetic manipulation, including recombination and p-element mobilisation
    -   Dissection and immunohistochemistry of Drosophila adult brains
    -   Confocal microscopy
    -   Microinjection for Drosophila embryonic transformation, transformation screening,     genotyping and balancing
    -   Advanced molecular biology techniques, including cloning and sequence analysis,     nucleic acid extraction, plasmid transformation, qPCR and in-situ hybridization.
    -   Cloning, design and generation of Drosophila mutants, including CRISPR techniques
    -   Experience with literature search, designing, planning, carrying out experiments and     data analysis
  • Able to work and communicate effectively with others
  • Able to plan tasks independently
  • Committed and motivated

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice.

Interested candidates are to apply through:
https://astar.aqayo.com/apply/42ea444-20/Research_Officer_SC_Lab


We regret that only shortlisted applicants will be notified.





Research Officer Position

Date available: immediate

Date posted: 13, October 2015

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences funded by the Agency for Science, Technology and Research (A*STAR). Its mission is to develop and foster a vibrant research culture for cutting-edge basic biomedical sciences. IMCB's research activities focus on the areas of Animal Models of Development and Disease, Cancer Genetics and Therapeutics, Cell Biology in Health and Disease, and Structural Biology and Drug Discovery. IMCB is continuously looking out for talented people to contribute to its success.

A research officer position is immediately available at the Monoclonal Antibody Unit in IMCB. The successful applicant will be primarily involved in a project studying hepatitis viral infection of mice but is required to assist in other projects whenever necessary. A 1-year contract will be offered in the first instance.

The successful candidate must be stimulated by interdisciplinary discussions and be motivated to develop and carry out strategies that assess outcomes of specific mission oriented research.

Requirements:

    • At least a Bachelor's degree (preferably with honours) in Biological Sciences or related fields
    • Must be able to communicate well in English.
    • Research experience in virology and/or cell biology is preferred.
    • Prior experience in mouse experimentation is preferred.
    • Willing to work with live virus and mouse models.
    • Able to assist in laboratory administrative and management tasks including procurement and safety issues.
    • Able to work in a team and conduct independent research with excellent analytical, technical and problem solving skills.

    Read more about our work at: http://www.imcb.a-star.edu.sg/php/ittd-mau.php

    Interested candidates are to email a detailed CV that includes two referees to recruit@imcb.a-star.edu.sg. We regret that only shortlisted applicants will be notified.