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  Principal Investigators   IMCB JUNIOR Investigators   IMCB Independent Fellow   RESEARCH FELLOWS   research/Lab Officers   OTHER Opportunities    
     
 


Positions in Next-Generation sequencing @ IMCB

Date available: Immediate

Date posted: 26 August 2014

Description:

The Institute of Molecular and Cell Biology (IMCB) is currently looking for a Research Scientist/ Fellow/ Officer (Next-Generation sequencing/wet lab) and a Research Fellow/ Officer (Bioinformatician).

1. Research Scientist/ Fellow/ Officer (Next-Generation sequencing/wet lab)

The successful candidate will play an essential role in research and development within IMCB, interacting with multiple scientists, and enabling the use of the NGS platform. He/She will be part of a highly motivated team of scientists and technicians, but is expected to work independently.

Responsibilities will include the preparation, development and optimization of genome- and transcriptome-sequencing (Next-Generation sequencing) libraries and protocols; managing and coordinating collaborations with research groups, participating in experimental design and contributing to final written reports.

Requirements:

  • Master or PhD degree in Biomedical Sciences.
  • Five years or more work experience in a molecular biology lab.
  • Experience with next-gen sequencing is preferred.
  • Familiarity with DNA sequencing, Primer-design softwares.

2. Research Fellow/ Officer (Bioinformatician)

The successful candidate will work in a dynamic multi-disciplinary team and collaborate with other bioinformaticians and biologists in supporting NGS research projects.

Responsibilities will include running pipelines for extracting and analyzing massive parallel sequencing data from Next Generation Sequencers; curate and integrating in-house genomic (ChIP-seq, DNA-seq, exon-seq, RNA-seq et al.) data sets.

Requirements:

  • Master or PhD Degree in Bioinformatics, Computer Science, or related disciplines.
  • Work experience in a computational or molecular biology lab.
  • Background in scripting languages, Perl/python, SQL, and Unix programming is essential.
  • Good working knowledge and experience in data management for genomic (ChIP-seq, DNA-seq, RNA-seq et al.) will be an advantage.

Interested applicants should send a CV and a brief description of research experience to:
Dr. Ernesto 
GUCCIONE
eguccione@imcb.a-star.edu.sg

or to
Human Resources Department, Institute of Molecular and Cell Biology, 61 Biopolis Drive, Level 2, #02-02, Proteos Building, Singapore 138673; Fax: 6779 1117 or email to :
recruit@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.


Laboratory Officer position

Date available: Immediate

Date posted: 21 August 2014

Description:
The Advanced Molecular Pathology Laboratory provides key support in conducting cutting-edge biomedical research and development with specific focus on rodent histology. As part of the dynamic team, you will be responsible for providing services in this laboratory to support the needs of researchers.

Responsibilities:

  • Operate specialised laboratory equipment to provide service to the research community.
  • Provide high quality technical services to researchers in the areas of complex tissue collection and processing procedures, as well as other laboratory procedures such as necropsy, embedding, cryotomy, microtomy, staining, etc.
  • Maintain equipment, consumables, etc in good working order to ensure an uninterrupted service whenever possible.
  • Handle routine laboratory administration.

Requirements:

  • Diploma in Life Sciences, Biological Sciences or a related field.
  • Good basic laboratory skills and manual dexterity.
  • Familiarity with histopathology techniques and GLP would be an advantage.
  • Meticulous and organised with an ability to multi-task
  • Good communication, interpersonal and analytical skills.
  • Able to work independently and as a team in a fast-paced environment.
  • Willing to work in a service based environment and provide technical service support

Interested applicants are welcome to write in with a detailed resume, supporting documents and contact numbers to: recruit@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.


Laboratory/Research Officer position

Date available: Immediate

Date posted: 19 August 2014

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences funded by the Agency for Science, Technology and Research (A*STAR). Its vision is to be a premier molecular biology and cell institute with increasing focus on addressing the mechanistic basis of human diseases. IMCB’s research activities focus on the areas of Animal Models of Development and Disease, Cancer Genetics and Therapeutics, Cell Biology in Health and Disease, and Structural Biology and Drug Discovery. IMCB is continuously looking out for talented people to contribute to its success.l

The monoclonal antibody unit (MAU) in IMCB aims to generate and characterize monoclonal antibodies that are useful for translational research.  We are now inviting suitable candidates to apply for the following position:

Laboratory / Research Officer

Responsibilities:

  • Perform or assist in molecular biology and biochemistry experiments such as cell culture, cloning, protein expression and purification, Western blot and immunofluorescence analyses
  • Lab maintenance: roles include placing orders, fixed assets management, performing preventive maintenance and calling for repairs.
Requirements:
  • Candidates should possess a Diploma or Bachelor of Science
  • Candidate should be comfortable in handling live animals (mice)
  • Candidate should have good organizational skills and good work attitude
  • Candidate should have good technical and communication skills

Interested applicants are welcome to write in with a detailed resume, supporting documents and contact numbers to: recruit@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.


Research Assistant position

Date available: Immediate

Date posted: 8 July 2014

Research Assistant in the Laboratory of Asst Prof Wang Xiaomeng, LKCMedicine, NTU and Laboratory of Prof Hong Wanjin, IMCB, A*STAR 

Lee Kong Chian School of Medicine (LKCMedicine) is a new joint medical school by Imperial College London and Nanyang Technological University, Singapore. It was established in September 2010 and will operate from two campuses – Yunnan Campus at Nanyang Technological University and a new campus to be built at Novena. Its primary healthcare partner is the National Healthcare Group (NHG) which comprises an integrated network of primary healthcare polyclinics, acute care hospitals such as Tan Tock Seng Hospital, and national specialty centres. Lee Kong Chian School of Medicine will deliver a new five-year undergraduate medical programme resulting in a joint degree (MBBS) awarded by Imperial College London and Nanyang Technological University. The first cohort of 50 students has started in August 2013.

The Institute of Molecular and Cell Biology (IMCB) was launched in 1985 to develop and support biomedical R&D capabilities in Singapore. Its original vision was to foster a vibrant research culture to enable cutting edge discoveries and nurture high-quality talent. Today, IMCB has established itself as a premier molecular & cell biology institute, addressing the mechanistic basis of human diseases. IMCB Discovery research includes Cell Biology in Health and Disease; Animal Models of Development & Disease; Cancer & Stem Cell Genetics & Genomics; and Structural Biology & Drug Discovery. IMCB Translational research includes Humanized Model Organisms for Human Diseases; Systems Approach for Disease Target Identification & Validation; and Protein Engineering & Antibody Development for Diagnostics & Therapeutics. Research in IMCB is supported by cutting edge infrastructure and facilities including Quantitative Proteomics; Humanized Mice; Mouse Models of Human Cancer; Protein Crystallography X-Ray; Zebrafish for Drug Metabolism & Toxicology; Advanced Molecular Histopathology; Imaging & Electron Microscopy; DNA Sequencing; Medicinal Chemistry & Drug Development; Genome-wide RNAi screens; and Monoclonal Antibody.

We are currently recruiting a Research Assistant who will be working with Dr Wang Xiaomeng Wang, Assistant Professor at LKCMedicine/Joint Principal Investigator at IMCB and Prof Hong Wanjin, Executive Director, IMCB.

The appointed Research Assistant will be involved in studying the TGFβ mediated angiogenesis using the state-of-art in vitro, ex vivo and in vivo technologies. The ultimate goal is to develop novel treatment strategies

This Research Assistant will have the opportunity to work in a dynamic environment with experienced molecular and cell biologists, and geneticists. The appointed Research Assistant will also have access to leading edge core facilities.

Successful candidates will have a Bachelor or Master’s degree in Biology, with a few years of experience in the areas of cell and molecular biology, and rodent experimental genetics. S/He should be comfortable in the operational aspects of a research laboratory, the technical management of research projects and in the collaborations between different research groups. In addition, the mastery of informatics tools used in a biology research laboratory would also be required.

Application Procedure:
Please send in applications to Dr Andrew Ang, Director, Research Administration and Support Services (email: angdrewang@ntu.edu.sg) or recruit@imcb.a-star.edu.sg with your CV, list of publications, statement of research interests and names of three references at your earliest convenience. For further queries, you may write to Dr. Xiaomeng Wang (email: wangxiaomeng@ntu.edu.sg) and Prof Wanjin Hong (email: mcbhwj@imcb.a-star.edu.sg).

Only shortlisted candidates will be notified.




Research Officer position

Date available: Immediate

Date posted: 20 June, 2014

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences funded by the Agency for Science, Technology and Research (A*STAR). Its mission is to develop and foster a vibrant research culture for cutting-edge basic biomedical sciences. IMCB’s research activities focus on the areas of Animal Models of Development and Disease, Cancer Genetics and Therapeutics, Cell Biology in Health and Disease, and Structural Biology and Drug Discovery. IMCB is continuously looking out for talented people to contribute to its success. 

The laboratory is looking for a motivated Research Officer who will support the effort in conducting cutting-edge biomedical research, assist researchers in their research projects, provide infrastructure support for researchers such as laboratory supplies and perform functions like procurement and inventory control for the laboratory and also work with mice. Further information is available at the following website: http://www.imcb.a-star.edu.sg/php/vinayt.php

Requirements:
- Applicants should possess at least a basic degree in biology or related fields.
- Hands-on experience in molecular biology and/or animal handling is required.
- Candidates should have good organizational skills and good work attitude.
- Candidates interested in working in research laboratories are invited to apply.

Interested applicants are welcome to fax or write in with a detailed resume, supporting documents and contact numbers by 15 July 2014 to recruit@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.

 


Research Officer position

Date available: Immediate

Date posted: 4 June, 2014

One Research Officer position is immediately available at IMCB Metabolic Syndrome and Cancer Risk Laboratory. The successful applicant will be involved in an industry-funded dermatologic research project. 

Applicants can visit the lab website to find out more http://www.sbs.ntu.edu.sg/aboutus/Faculty/NSTan/Pages/Home.aspx

Requirements:
BSc or BSc (Hon) Life Sciences/Biomedical Sciences.
Prior experience with 3D organotypic skin culture is necessary.
Committed and able to work flexible hours.
Excellent organizational skills and have experience in lab management.

Interested candidates are welcome to write in with a detailed resume, supporting documents and contact numbers to Andrew Tan (nstan@imcb.a-star.edu.sg)

We regret that only shortlisted applicants will be notified.

 


Research Officer position

Date available: Immediate

Date posted: 3 June, 2014

A Research officer position is available immediately at the IMCB Epigenetics and Cell fates Laboratory. The laboratory is interested in dissecting the genetic and epigenetic mechanisms regulating cell fate changes, while developing novel tools and strategies in deriving differentiated cell types via defined factors reprogramming.

Applicants with relevant background in Molecular Biology, Cell Biology, Biochemistry or related fields are invited to apply. Experience with Stem cells, Genomics or animal works would be highly desirable though not essential. Successful candidates must be interested in Translational research,highly motivated, and be able to work in an interdisciplinary environment.

Requirements:
- M.Sc. or B.Sc. (Hons) from a well-recognized institution in Life Sciences/Biomedical Sciences
- Committed and able to work flexible hours
- Expertise in cell culture, RNA extraction and other Molecular Biology techniques.
- Excellent analytical, technical and problem solving skills
- Excellent organizational skills and have experience in lab management

Interested candidates are asked to send a cover letter detailing your research motivations, CV, and the names and email addresses of three references to Jonathan Loh (yhloh@imcb.a-star.edu.sg). Applicants can visit the lab website to find out more (http://www.imcb.a-star.edu.sg/php/jl.php).

References:

  1. Gore A et al. Somatic coding mutations in human induced pluripotent stem cells. (2011)
    Nature 471, 63-67.
  2. Agarwal S et al. Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients. (2010) Nature 464, 292-296.
  3. Loh YH et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. (2006) Nature Genetics 38, 431–440.

 



Laboratory /Research Officer

Date available: Immediate

Date posted: 2 June 2014

The Humanized Mouse Unit is looking for a motivated Laboratory/Research Officer who willsupport the efforts in research and development of new humanized mouse models. The successful applicant is also encouraged to actively participate in R&D projects, acquire the relevant skills, and contribute to the project team.

Requirements:

  • Applicants should possess a Diploma or a Degree in Biology/Life Sciences.
  • Applicants should be capable of performing routine mouse husbandry and other mouse-related work.
  • Applicants should be capable of performing routine research techniques such as tissue culture, ELISA and FACS.
  • Applicants should have good organizational skills, ability to multi-task and a good work attitude.

Interested applicants are welcome to fax or write in with a detailed resume, supporting documents and contact numbers to: Human Resources Department, Institute of Molecular and Cell Biology, 61 Biopolis Drive, Level 2, #02-03, Proteos Building, Singapore 138673; Fax: 6779 1117 or email to : recruit@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.



Laboratory biologist position

Date available: Immediate

Date posted: 14 May, 2014

Position of a laboratory biologist is currently available to assist in a project that aims to understand the cellular and genetic basis of cilia formation and then extrapolate the findings to human ciliary disorders. Cilia are microtubule based organelles that have manifold functions in animal development and physiology. Further information is available at the following website: http://www.imcb.a-star.edu.sg/php/sudipto.php

Prospective candidates should have a Diploma or degree in a relevant field of the Life Sciences like molecular biology, biochemistry, developmental biology, cell biology or genetics. The applicants should have good academic records as well as enthusiasm and genuine passion and commitment for pursuing research in cell and developmental biology. Technical competence with standard molecular biology, protein chemistry, cell culture and microscopy techniques is essential. Experience in the handling of zebrafish adults and embryos is preferred, but not essential. Interested applicants are welcome to fax or write in with a detailed resume, supporting documents and contact numbers by 30 June 2014 to recruit@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.



Research Officer position

Date available: Immediate

Date posted: 8 May 2014

A Research officer position is available immediately at the IMCB Epigenetics and Cell fates Laboratory. The laboratory is interested in dissecting the genetic and epigenetic mechanisms regulating cell fate changes, while developing novel tools and strategies in deriving differentiated cell types via defined factors reprogramming.

Applicants with relevant background in Molecular Biology, Cell Biology, Biochemistry or related fields are invited to apply. Experience with Stem cells, Genomics or animal works would be highly desirable though not essential. Successful candidates must be interested in Translational research,highly motivated, and be able to work in an interdisciplinary environment.

Requirements:

  • M.Sc. or B.Sc. (Hons) from a well-recognized institution in Life Sciences/Biomedical Sciences
  • Committed and able to work flexible hours
  • Expertise in cell culture, RNA extraction and other Molecular Biology techniques.
  • Excellent analytical, technical and problem solving skills
  • Excellent organizational skills and have experience in lab management

Interested candidates are asked to send a cover letter detailing your research motivations, CV, and the names and email addresses of three references to Jonathan Loh (yhloh@imcb.a-star.edu.sg). Applicants can visit the lab website to find out more (http://www.imcb.a-star.edu.sg/php/jl.php)

References:

  1. Gore A et al. Somatic coding mutations in human induced pluripotent stem cells. (2011)
    Nature 471, 63-67.
  2. Agarwal S et al. Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients. (2010) Nature 464, 292-296.
  3. Loh YH et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. (2006) Nature Genetics 38, 431–440.





Laboratory/Research Officer position

Date available: Immediate

Date posted: 11 April 2014

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences funded by the Agency for Science, Technology and Research (A*STAR). Its mission is to develop and foster a vibrant research culture for cutting-edge basic biomedical sciences. IMCB’s research activities focus on the areas of Animal Models of Development and Disease, Cancer Genetics and Therapeutics, Cell Biology in Health and Disease, and Structural Biology and Drug Discovery. IMCB is continuously looking out for talented people to contribute to its success. We are now inviting suitable candidates to apply for the following position:

Laboratory/Research Officer
Our laboratory specializes in conducting cutting-edge biomedical research in the field of RNA biology. You will have the opportunity to be familiar with molecular biology work, as well as genome-wide-level research such as ribosome profiling and RNA-Seq.

Responsibilities:

  • Perform molecular biology research, especially RNA work
  • Perform bioinformatics analysis for genome-wide data
  • Provide technical support
  • Perform lab administrative tasks such as purchasing
Requirements:
  • Diploma or Degree in Biological Sciences or equivalent
  • Highly motivated individual with an inquisitive mind
  • Strong organizational skills
  • Prior experience in molecular biology and cell culture techniques is preferred, but not essential
  • Familiarity with bioinformatics and programming would be an asset

Interested applicants are welcome to submit a detailed resume, supporting documents and contact information to:

Human Resources Department, Institute of Molecular and Cell Biology, 61 Biopolis Drive, Level 2, #02-03, Proteos, Singapore 138673; Fax: 6779 1117 or email: recruit@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.



Research Officer position

Date available: 1 April 2014

Date posted: 4 March, 2014

The Institute of Molecular and Cell Biology (IMCB) is a leading research institute in biological sciences funded by the Agency for Science, Technology and Research (A*STAR). Its mission is to develop and foster a vibrant research culture for cutting-edge basic biomedical sciences. IMCB’s research activities focus on the areas of Animal Models of Development and Disease, Cancer Genetics and Therapeutics, Cell Biology in Health and Disease, and Structural Biology and Drug Discovery. IMCB is continuously looking out for talented people to contribute to its success. We are now inviting suitable candidates to apply for the following position:

Research Officer
The Collaborative and Translational Unit for HFMD specializes in translational antiviral research developments for human enteroviruses.  You will have the opportunity to be familiar with molecular virology as well as high throughput screening technologies for antiviral discovery and development.

Responsibilities:

  • Perform research using molecular biology, virology and basic biochemical methods.
  • Perform research using animal models of infection.
  • Provide technical support for research activities in the unit.
  • Perform laboratory administrative and management tasks that include purchasing and safety management.
Requirements:
  • Degree in Life Sciences or equivalent
  • Highly motivated individual with an inquisitive mind
  • Strong organizational and management skills
  • Prior experience in molecular biology, Virology and cell culture techniques is preferred

Interested applicants are welcome to submit a detailed resume, supporting documents and contact information to: recruit@imcb.a-star.edu.sg

We regret that only shortlisted applicants will be notified.