Boon Seng SOH
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  Recent Publications  

Zheng D, Soh BS, Yin L, Hu G, Chen Q, Choi H, Han J, Chow VT, Chen J.
Differentiation of club cells to alveolar epithelial cells in vitro.
Sci Rep. 2017 Jan 27;7:41661. doi: 10.1038/srep41661.

Tan HN, Tay ZY, Soh BS.
Intervention for cardiac repair: A clinical perspective.
Curr Stem Cell Res Ther. 2017 Jan 12. [Epub ahead of print]

Soh BS, Ng SY, Wu H, Buac K, Park JH, Lian X, Xu J, Foo KS, Felldin U, He X, Nichane M, Yang H, Bu L, Li RA, Lim B, Chien KR.
Endothelin-1 supports clonal derivation and expansion of cardiovascular progenitors derived from human embryonic stem cells.
Nat Commun. 2016 Mar 8;7:10774. doi: 10.1038/ncomms10774.

Ng SY*, Soh BS*, Rodriguez-Muela N, Hendrickson DG, Price F, Rinn JL, Rubin LL.
Genome-wide RNA-seq of human motor neurons implicates selective ER stress activation in Spinal Muscular Atrophy.
Cell Stem Cell. 2015 Aug 26. pii: S1934-5909(15)00358-6. (*co-first author)

Soh BS*, Buac K*, Xu H*, Li E, Ng SY, Wu H, Chmielowiec J, Jiang X, Bu L, Li RA, Cowan C, Chien KR.
N-cadherin prevents the premature differentiation of second heart field progenitors in the pharyngeal mesoderm microenvironment.
Cell Res. 2014 Dec;24(12):1420-32. (Featured article) (*co-first author).

Tam WL, Lu H, Buikhuisen J, Soh BS, Lim E, Reinhardt F, Wu ZJ, Krall JA, Bierie B, Guo W, Chen X, Liu XS, Brown M, Lim B, Weinberg RA.
Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells.
Cancer Cell. 2013 Sep 9;24(3):347-64.

Ng SY, Bogu GK, Soh BS, Stanton LW.
The long non-coding RNA RMST interacts with SOX2 to regulate neurogenesis.
Mol. Cell. 2013 Aug 8;51(3):349-59.

Ng SY, Lin L, Soh BS, Stanton LW.
Long non-coding RNAs in development and disease of the central nervous system.
Trends Genetics. 2013 Aug;29(8):461-8.

Soh BS, Wu H, Chien KR.
Cardiac regenerative medicine 2.0.
Nat Biotechnol. 2013 Mar;31(3):209-11.

Soh BS*, Zheng D, Yeo SL, Yang H, Ng SY, Wong LH, Zhang W, Li P, Nichane M, Asmat A, Wong PS, Wong PC, Su LL, Mantalaris A, Lu J, Xian W, McKeon F, Chen J, Lim EH* and Lim B*.
CD166(pos) Subpopulation From Differentiated Human ES and iPS Cells Support Repair of Acute Lung Injury.
Mol Ther. 2012 Dec;20(12):2335-46. (*Co-corresponding)

Zhang WC, Shyh-Chang N, Yang H, Rai A, Umashankar S, Ma S, Soh BS, Sun LL, Tai BC, Nga ME, Bhakoo KK, Jayapal SR, Nichane M, Yu Q, Ahmed DA, Tan C, Sing WP, Tam J, Thirugananam A, Noghabi MS, Huei Pang Y, Ang HS, Robson P, Kaldis P, Soo RA, Swarup S, Lim EH, Lim B.
Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis.
Cell. 2012 Jan 20;148(1-2):259-72.

Chia NY, Chan YS, Feng B, Lu X, Orlov YL, Moreau D, Kumar P, Yang L, Jiang J, Lau MS, Huss M, Soh BS, Kraus P, Li P, Lufkin T, Lim B, Clarke N, Bard F, Ng HH.
A genome-wide RNAi screen reveals determinants of human ES cell identity.
Nature. 2010 Nov 11;468(7321):316-20.

Han J, Yuan P, Yang H, Zhang J, Soh BS, Li P, Lim SL, Cao S, Tay J, Orlov YL, Lufkin T, Ng HH, Tam WL, Lim B.
Tbx3 improves the germ-line competency of induced pluripotent stem cells.
Nature. 2010 Feb 25;463(7284):1096-100.

Soh BS, Song CM, Vallier L, Li P, Choong C, Yeo BH, Lim EH, Pedersen RA, Yang HH, Rao M, Lim B.
Pleiotrophin enhances clonal growth and long-term expansion of human embryonic stem cells.
Stem Cells. 2007 Dec;25(12):3029-37.

Zhang J, Tam WL, Tong GQ, Wu Q, Chan HY, Soh BS, Lou Y, Yang J, Ma Y, Chai L, Ng HH, Lufkin T, Robson P, Lim B.
Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1.
Nat Cell Biol. 2006 Oct;8(10):1114-23.

Lee YK, Chew PF, Soh BS, et al.
Enhancing phagocytic activity of hemocytes and disease resistance in the prawn Penaeus merguiensis by feeding Spirulina platensis.
J. App Phycology 2003 Jul; 15 (4): 279-287.

Loke P, Goh LL, Soh BS, Yeow P and Sim TS.
Purification and characterization of recombinant malate synthase enzymes from Streptomyces Coelicolor A3 (2) and Streptomyces clavuligerus NRRL 3585.
J. Ind microbial Biotechnol. 2002 Apr; 28(4): 239-43

Soh BS, loke P and Sim TS.
Cloning, heterologous expression and purification of an isocitrate lyase from Streptomyces clavuligerus NRRL 3585.
Biochim Biophys Acta. 2001 Dec 3; 1522(2): 112-7

Lee YK, Soh BS and Wu JH.
Quantitative assessment of phagocytic activity of hemocytes in prawn, Penaeus merguiensis by flow cytometric analysis.
Cytometry. 2001 Jan 1;43(1):82-85


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