I. Tan, J. Yong, J.M. Dong, L. Lim. and T. Leung.
A Tripartite Complex containing MRCK Modulates Lamella Actomyosin Retrograde Flow.
Cell 135 :123-136, 2008
Z-S Zhao, J.P. Lim, Y-W Ng, L. Lim and E. Manser.
The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A
Mol. Cell 20: 237-249, 2005
K.J. M. Marler, R. Kozma, S. Ahmed, J.M. Dong, C. Hall and L. Lim.
Outgrowth of Neurites from N1E-115 Neuroblastoma Cells is prevented on repulsive substrates through the action of PAK.
Mol. Cell. Biol. 25: 5226-5241, 2005
Z-S Zhao and E. Manser.
PAK and other Rho-associated kinases-effectors with surprisingly diverse mechanisms of regulation.
Biochem. J. 386: 201-214, 2005
T.H. Loo, Y-W. Ng, L. Lim and E. Manser.
GIT1 activates PAK through a mechanism independent of p21 binding.
Mol. Cell. Biol 24 :3849-59, 2004
C.G. Koh, E.J. Tan, E. Manser and L. Lim
The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/ threonine phosphatases of the PP2C family.
Current Biol. 12: 317-21, 2002.
Z-S. Zhao, E. Manser, T.H. Loo and L. Lim
Coupling of the PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly.
Mol. Cell. Biol. 20: 6354-63, 2000.
X-Q. Chen, I. Tan, T. Leung and L. Lim
The myotonic dystrophy kinase-related Cdc42-binding kinase is involved in the regulation of neurite outgrowth in PC12 cells.
J. Biol. Chem. 274: 19901-5, 1999.
E. Manser, T-H. Loo, C-G. Koh, Z-S. Zhao, X-Q. Chen, L. Tan, I. Tan, T. Leung and L. Lim
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors.
Mol. Cell. 1: 183-92, 1998.
T. Leung, X-Q. Chen, I. Tan, E. Manser and L. Lim
Myotonic dystrophy kinase-related Cdc42- binding kinase (MRCK) acts as a Cdc42 effector in promoting cytoskeletal reorganization.
Mol. Cell. Biol. 18: 130-40, 1998.
R. Kozma, S. Sarner, S. Ahmed and L. Lim
Rho Family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1 and acetylcholine, and collapse induced by RhoA and Lysophosphatidic acid.
Mol. Cell. Biol. 17: 1201-11, 1997.
T. Leung, X-Q. Chen, E. Manser and L. Lim
The p160 RhoA-binding kinase ROKα is a member of a kinase family and is involved in the reorganization of the cytoskeleton.
Mol. Cell. Biol. 16: 5313-27, 1996.
R. Kozma, S. Ahmed, A. Best and L. Lim
The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 cells.
Mol. Cell. Biol. 15: 1942-52, 1995.
E. Manser, T. Leung, H. Salihuddin, Z-S. Zhao and L. Lim
A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 367: 40-6 , 1994.